anti-Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1) Antibodies

May play a role in vesicle formation and transport (By similarity).. Additionally we are shipping PACSIN1 Proteins (7) and PACSIN1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PACSIN1 29993 Q9BY11
PACSIN1 23969 Q61644
PACSIN1 29704 Q9Z0W5
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Top anti-PACSIN1 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN184665 (1µg/ml) staining of Human Brain (hippocampus) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-PACSIN1 Antibody Titration:  2.5ug/ml  ELISA Titer:  1:62500  Positive Control:  Transfected 293T 100 μL 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Anti-PACSIN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962676 concentration 41396 ug/ml. Anti-PACSIN1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962676 concentration 41396 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Goat Un-conjugated WB   0.1 mg 4 to 8 Days
$462.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of mouse cerebellum and mouse brain cell lines, using PACSIN1 antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg 2 to 3 Days
$515.63
Details

Top referenced anti-PACSIN1 Antibodies

  1. Rat (Rattus) Polyclonal PACSIN1 Primary Antibody for ICC, WB - ABIN1742407 : Wahl, Katiyar, Schmitz: A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PACSIN1 Primary Antibody for ELISA, WB - ABIN546778 : Modregger, DiProspero, Charles, Tagle, Plomann: PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains. in Human molecular genetics 2002 (PubMed)

  3. Human Polyclonal PACSIN1 Primary Antibody for IHC (p), ELISA - ABIN544257 : Sumoy, Pluvinet, Andreu, Estivill, Escarceller: PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family. in Gene 2001 (PubMed)

  4. Human Polyclonal PACSIN1 Primary Antibody for ICC, IF - ABIN4343361 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against PACSIN1 Interaction Partners

Human Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1) interaction partners

  1. PACSIN1 and EHD1 assemble membrane tubules from the developing intracellular cilium that attach to the plasma membrane, creating an extracellular membrane channel to the outside of the cell.

  2. Specifically, CKS1B and MAP2K5 significantly inhibited hepatitis C viral RNA replication. PACSIN1, by contrast, inhibited hepatitis C virus infection by decreasing the level of viral protein p7.

  3. syndapin I functions reflected direct, SH3 domain-mediated associations and functional interactions with ProSAP1/Shank2.

  4. Data indicate that the structural capacity of N17 to fold back toward distal regions within huntingtin requires an interacting protein, protein kinase C and casein kinase 2 substrate in neurons 1 (PACSIN1).

  5. Pacsin-1 plays a versatile role in sculpting cellular membranes that is likely dependent both on protein structure and membrane properties.

  6. PACSIN1 represents a pDC-specific adaptor molecule that plays an important role in the TLR7/9-mediated type I IFN responses by pDCs in vitro and in vivo.

  7. Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation

  8. PACSIN 1 (1-344) was crystallized & diffracted to resolution of 3.0 A. The crystal belonged to space group C2, with unit-cell parameters a=158.65, b=87.38, c=91.76 A, alpha=90.00, beta=113.61, gamma=90.00 degrees. There are 2 molecules in asymmetric unit.

  9. The regulated deformation of membranes and promotion of tubule constrictions by Pacsin suggests a more versatile function of these proteins in vesiculation and endocytosis.

Mouse (Murine) Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1) interaction partners

  1. Overall, the global native-KCC2 interactome and subsequent characterization revealed PACSIN1 as a novel and potent negative regulator of KCC2.

  2. Structure and function analysis reveals a requirement for the PACSIN1 F-BAR and SH3 domains in controlling NMDA receptor-dependent processes.

  3. syndapin I functions reflected direct, SH3 domain-mediated associations and functional interactions with ProSAP1/Shank2.

  4. The SdpI-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta.

  5. upon BDNF signaling PACSIN 1 is phosphorylated by CK2 which is essential for spine formation

  6. PACSIN1 is an important Tau binding partner in regulating microtubule dynamics and forming axonal plasticity.

  7. These results implicate Pak5 in Pacsin1- and Synaptojanin1-mediated synaptic vesicle trafficking.

  8. syndapin I acts as pivotal membrane anchoring factor for dynamins during regeneration of synaptic vesicles.

  9. These findings suggest a novel function for PACSIN proteins 1, 2, and 3 in dynamic microtubule nucleation.

PACSIN1 Antigen Profile

Protein Summary

May play a role in vesicle formation and transport (By similarity).

Gene names and symbols associated with PACSIN1

  • protein kinase C and casein kinase substrate in neurons 1 (PACSIN1) antibody
  • protein kinase C and casein kinase substrate in neurons 1 S homeolog (pacsin1.S) antibody
  • protein kinase C and casein kinase substrate in neurons 2 (pacsin2) antibody
  • protein kinase C and casein kinase substrate in neurons 1b (pacsin1b) antibody
  • protein kinase C and casein kinase substrate in neurons 1 (Pacsin1) antibody
  • A830061D09Rik antibody
  • fe25d06 antibody
  • H74 antibody
  • MGC84055 antibody
  • mKIAA1379 antibody
  • PACSIN1 antibody
  • SDPI antibody
  • sdpii antibody
  • syndapin antibody
  • wu:fe25d06 antibody
  • x-PACSIN2 antibody
  • zgc:114042 antibody

Protein level used designations for PACSIN1

protein kinase C and casein kinase substrate in neurons 1 , protein kinase C and casein kinase substrate in neurons 2 , protein kinase C and casein kinase substrate in neurons protein 1 , syndapin 1 , syndapin I , Syndapin I , dynamin PRD-interacting protein , dynamin proline-rich domain-interacting protein , sdpI , synaptic, dynamin-associated protein I , syndapin-I

GENE ID SPECIES
419903 Gallus gallus
447231 Xenopus laevis
496460 Xenopus (Silurana) tropicalis
619246 Danio rerio
718624 Macaca mulatta
100172814 Pongo abelii
29993 Homo sapiens
608087 Canis lupus familiaris
520488 Bos taurus
23969 Mus musculus
29704 Rattus norvegicus
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