anti-Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1) Antibodies

May play a role in vesicle formation and transport (By similarity).. Additionally we are shipping PACSIN1 Proteins (7) and PACSIN1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PACSIN1 29993 Q9BY11
PACSIN1 23969 Q61644
PACSIN1 29704 Q9Z0W5
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Top anti-PACSIN1 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184665 (1µg/ml) staining of Human Brain (hippocampus) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-PACSIN1 Antibody Titration:  2.5ug/ml  ELISA Titer:  1:62500  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-PACSIN1 Pab (ABIN392664) in HL-60 cell line lysate. PACSIN1 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Western blot analysis of anti-PACSIN1 Pab (ABIN392664) in mouse brain tissue lysate . PACSIN1 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), SimWes, WB Immunohistochemistry-Paraffin: PACSIN1 Antibody [NBP2-33756] - Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subset of non-germinal center cells. Immunohistochemistry-Paraffin: PACSIN1 Antibody [NBP2-33756] - lymph node 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: PACSIN1 Antibody [NBP1-87067] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunocytochemistry/Immunofluorescence: PACSIN1 Antibody [NBP1-87067] - Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-PACSIN1 Pab (ABIN392665) is used in Western blot to detect PACSIN1 in mouse brain tissue lysate. Western blot analysis of anti-PACSIN1 Antibody (Center)(ABIN392665) in Y79 cell line lysates (35 µg/lane). PACSIN1(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: PACSIN1 Antibody [NBP1-32324] - Sample(30 ug of whole cell lysate)A:MOLT4 7. 5% SDS PAGE, antibody diluted at 1:500. Western Blot: PACSIN1 Antibody [NBP1-32324] - Sample (20 ug of whole cell lysate) A: mouse brain 10% SDS PAGE; antibody diluted at 1:10000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Anti-PACSIN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962676 concentration 41396 ug/ml. Anti-PACSIN1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962676 concentration 41396 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Dog Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details

Top referenced anti-PACSIN1 Antibodies

  1. Rat (Rattus) Polyclonal PACSIN1 Primary Antibody for ICC, WB - ABIN1742407 : Wahl, Katiyar, Schmitz: A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PACSIN1 Primary Antibody for ICC, IF - ABIN4343361 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

  3. Human Polyclonal PACSIN1 Primary Antibody for ELISA, WB - ABIN257699 : Modregger, DiProspero, Charles, Tagle, Plomann: PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains. in Human molecular genetics 2002 (PubMed)

More Antibodies against PACSIN1 Interaction Partners

Human Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1) interaction partners

  1. Specifically, CKS1B (show CKS1B Antibodies) and MAP2K5 (show MAP2K5 Antibodies) significantly inhibited hepatitis C viral RNA replication. PACSIN1, by contrast, inhibited hepatitis C virus infection by decreasing the level of viral protein p7.

  2. syndapin I functions reflected direct, SH3 domain (show ITSN1 Antibodies)-mediated associations and functional interactions with ProSAP1/Shank2 (show SHANK2 Antibodies).

  3. Data indicate that the structural capacity of N17 to fold back toward distal regions within huntingtin (show HTT Antibodies) requires an interacting protein, protein kinase C (show PKC Antibodies) and casein kinase 2 substrate in neurons 1 (PACSIN1).

  4. Pacsin-1 plays a versatile role in sculpting cellular membranes that is likely dependent both on protein structure and membrane properties.

  5. PACSIN1 represents a pDC (show PNKD Antibodies)-specific adaptor molecule that plays an important role in the TLR7 (show TLR7 Antibodies)/9-mediated type I IFN responses by pDCs in vitro and in vivo.

  6. Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation

  7. PACSIN 1 (1-344) was crystallized & diffracted to resolution of 3.0 A. The crystal belonged to space group C2, with unit-cell parameters a=158.65, b=87.38, c=91.76 A, alpha=90.00, beta=113.61, gamma=90.00 degrees. There are 2 molecules in asymmetric unit.

Mouse (Murine) Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1) interaction partners

  1. Overall, the global native-KCC2 (show SLC12A5 Antibodies) interactome and subsequent characterization revealed PACSIN1 as a novel and potent negative regulator of KCC2 (show SLC12A5 Antibodies).

  2. Structure and function analysis reveals a requirement for the PACSIN1 F-BAR and SH3 domains in controlling NMDA receptor-dependent processes.

  3. syndapin I functions reflected direct, SH3 domain (show ITSN1 Antibodies)-mediated associations and functional interactions with ProSAP1/Shank2 (show SHANK2 Antibodies).

  4. The SdpI-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta.

  5. upon BDNF (show BDNF Antibodies) signaling PACSIN 1 is phosphorylated by CK2 (show CSNK2A1 Antibodies) which is essential for spine formation

  6. PACSIN1 is an important Tau binding partner in regulating microtubule dynamics and forming axonal plasticity.

  7. These results implicate Pak5 (show PAK7 Antibodies) in Pacsin1- and Synaptojanin1-mediated synaptic vesicle trafficking.

  8. syndapin I acts as pivotal membrane anchoring factor for dynamins during regeneration of synaptic vesicles.

PACSIN1 Antigen Profile

Protein Summary

May play a role in vesicle formation and transport (By similarity).

Gene names and symbols associated with PACSIN1

  • protein kinase C and casein kinase substrate in neurons 1 (PACSIN1) antibody
  • protein kinase C and casein kinase substrate in neurons 1 S homeolog (pacsin1.S) antibody
  • protein kinase C and casein kinase substrate in neurons 2 (pacsin2) antibody
  • protein kinase C and casein kinase substrate in neurons 1b (pacsin1b) antibody
  • protein kinase C and casein kinase substrate in neurons 1 (Pacsin1) antibody
  • A830061D09Rik antibody
  • fe25d06 antibody
  • H74 antibody
  • MGC84055 antibody
  • mKIAA1379 antibody
  • PACSIN1 antibody
  • SDPI antibody
  • sdpii antibody
  • syndapin antibody
  • wu:fe25d06 antibody
  • x-PACSIN2 antibody
  • zgc:114042 antibody

Protein level used designations for PACSIN1

protein kinase C and casein kinase substrate in neurons 1 , protein kinase C and casein kinase substrate in neurons 2 , protein kinase C and casein kinase substrate in neurons protein 1 , syndapin 1 , syndapin I , Syndapin I , dynamin PRD-interacting protein , dynamin proline-rich domain-interacting protein , sdpI , synaptic, dynamin-associated protein I , syndapin-I

GENE ID SPECIES
419903 Gallus gallus
447231 Xenopus laevis
496460 Xenopus (Silurana) tropicalis
619246 Danio rerio
718624 Macaca mulatta
100172814 Pongo abelii
29993 Homo sapiens
608087 Canis lupus familiaris
520488 Bos taurus
23969 Mus musculus
29704 Rattus norvegicus
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