Protein Phosphatase 4, Regulatory Subunit 2 Proteins
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
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Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-417) protein (His tag) Protein
Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-417) protein (His tag) Protein
Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-78) protein (His tag) Protein
Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-398) protein (His tag) Protein
Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-401) protein (His tag) Protein
Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-403) protein (His tag) Protein
Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-426) protein (His tag) Protein
Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) Protein Profile
Protein Summary
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair (By similarity). Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage- dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).
Gene names and symbols associated with PPP4R2
- protein phosphatase 4 regulatory subunit 2 (PPP4R2) antibody
- protein phosphatase 4, regulatory subunit 2 (Ppp4r2) antibody
- protein phosphatase 4, regulatory subunit 2a (ppp4r2a) antibody
- protein phosphatase 4 regulatory subunit 2 S homeolog (ppp4r2.S) antibody
- protein phosphatase 4 regulatory subunit 2 (ppp4r2) antibody
- protein phosphatase 4, regulatory subunit 2b (ppp4r2b) antibody
- BE691708 antibody
- C230060M08Rik antibody
- fe11b04 antibody
- PP4R2 antibody
- ppp4r2 antibody
- ppp4r2-B antibody
- wu:fa17h08 antibody
- wu:fc23g05 antibody
- wu:fe11b04 antibody
Protein level used designations for PPP4R2
serine/threonine-protein phosphatase 4 regulatory subunit 2 , serine/threonine-protein phosphatase 4 regulatory subunit 2-A , protein phosphatase 4, regulatory subunit 2 , serine/threonine-protein phosphatase 4 regulatory subunit 2-B , Serine/threonine-protein phosphatase 4 regulatory subunit 2
GENE ID | SPECIES |
---|---|
151987 | Homo sapiens |
232314 | Mus musculus |
297486 | Rattus norvegicus |
326723 | Danio rerio |
416098 | Gallus gallus |
446890 | Xenopus laevis |
496569 | Xenopus (Silurana) tropicalis |
693479 | Macaca mulatta |
100005419 | Danio rerio |
100352584 | Oryctolagus cuniculus |
504900 | Bos taurus |
100061905 | Equus caballus |
476556 | Canis lupus familiaris |
100626659 | Sus scrofa |
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- Protein Phosphatase 2, Regulatory Subunit B', delta Proteins
- Protein Phosphatase 2, Regulatory Subunit B', beta Proteins
- Protein Phosphatase 2, Regulatory Subunit B', alpha Proteins
- Protein Phosphatase 2, Regulatory Subunit B, gamma Proteins
- Protein Phosphatase 2, Regulatory Subunit B, beta Proteins
- Protein Phosphatase 2, Regulatory Subunit A, beta Proteins
- Protein Phosphatase 2, Regulatory Subunit A, alpha Proteins
- Protein Phosphatase 2, Catalytic Subunit, beta Isozyme Proteins
- Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme Proteins
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- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E Proteins
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G Proteins
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K Proteins
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