Protein tyrosine Phosphatase, Receptor Type, S Proteins (PTPRS)

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

• protein tyrosine phosphatase, receptor type S (PTPRS)
• protein tyrosine phosphatase, receptor type, S (Ptprs)

• AL022616 protein
• Larptp2 protein
• PTP protein
• PTP-NU3 protein
• PTPNU-3 protein
• Show all synonym aliases
• Ptprd protein
• Ptpsigma protein
• Ptpsigma. protein
• Ptpt9 protein
• R-PTP-S protein
• Rptpd protein
• RPTPsigma protein

R-PTP-S , R-PTP-sigma , protein tyrosine phosphatase PTPsigma , protein tyrosine phosphatase, receptor type, sigma , receptor-type tyrosine-protein phosphatase S , receptor-type tyrosine-protein phosphatase sigma , Receptor-type tyrosine-protein phosphatase sigma , tissue-specific protein tyrosine phosphatase , LAR-PTP2 , leukocyte common antigen-related protein-tyrosine phosphatase 2 , leukocyte common antigen-related proten-tyrosine phosphatase 2 , protein tyrosine phosphatase, receptor type, D