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May play a role in anteroposterior axis elongation.. Additionally we are shipping PRTG Proteins (7) and PRTG Kits (1) and many more products for this protein.
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We found that a burden of low-frequency coding variants in N4BP2 (show N4BP2 Antibodies), CDSN (show CDSN Antibodies), PRTG, and AHRR (show CYP1A1 Antibodies) were associated with increased risk of Nonsyndromic cleft lip with or without cleft palate (NSCL (show NHLH1 Antibodies)/P) . Low-frequency variants in other genes were associated with decreased risk of NSCL (show NHLH1 Antibodies)/P. These results demonstrate that low-frequency variants contribute to the genetic etiology of NSCL (show NHLH1 Antibodies)/P
PRTG is regulated by miRNA9, plays an inhibitory action on survival of chondroblasts and articular chondrocytes during chondrogenesis and osteoarthritis pathogenesis.
Identified association of attention deficit hyperactivity disorder (ADHD) to Protogenin (PRTG), a gene that potentially plays a role in cell migration and axon growth.
Overexpression of Prtg and Radil (show Radil Antibodies) activates alpha5beta1-integrins to high-affinity conformational forms.
This study showed that Prtg, which is a highly expressed gene in the E10.5 mouse mandible, using a cDNA subtraction method between mandibles at E10.5 and E12.0.
these results suggested that expression of PRTG defines a stage between pluripotent epiblasts and committed neural progenitors, and its signaling plays a critical role in suppressing premature neuronal differentiation during early neural development.
Protogenin expression is restricted to posterior neural plate and mesoderm, with an anterior limit at the level of the rhombencephalon.
May play a role in anteroposterior axis elongation.
immunoglobulin superfamily, DCC subclass, member 5
, protein Shen-Dan
, protogenin homolog (Gallus gallus)
, protogenin A