anti-Pyruvate Dehydrogenase Complex, Component X Antibodies

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A.

Data Quality
  • 2
  • 26
Type
  • 64
    Primary antibodies
Antigen
  • 64
Reactivity
  • 61
  • 31
  • 24
Application
  • 44
  • 17
  • 13
  • 10
  • 10
Host
  • 58
  • 3
  • 2
  • 1
Clonality
  • 63
  • 1
Clone
  • 1
Binding Specificity
  • 4
  • 3
  • 3
  • 2
  • 2
Conjugate
  • 43
  • 2
  • 2
  • 2
  • 2
Isotype
  • 33
  • 4
Format
  • 50
  • 1
64 Products
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN5014241
$245.00
100 μL
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
ReactivityMouse (Murine)
Application ICC, IHC, WB
Order details Cat. No. ABIN5014240
$252.00
100 μL
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
ReactivityHuman
Application IF/ICC, IHC, IP, WB
Order details Cat. No. ABIN2922754
$436.16
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityMouse (Murine)
Application IF/ICC, IHC, IP, WB
Order details Cat. No. ABIN2922755
$450.23
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityHuman
Application IHC (p), ELISA, WB
Order details Cat. No. ABIN544818
$431.43
400 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IF, WB
Order details Cat. No. ABIN521742
$440.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IF, WB
Order details Cat. No. ABIN6145384
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN185389
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application IP, WB
Order details Cat. No. ABIN948658
$425.71
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IHC (p), ELISA, WB
Order details Cat. No. ABIN547434
$451.43
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine)
Application EIA, WB
Order details Cat. No. ABIN4620452
$792.00
0.1 mg
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine)
Application EIA, IHC (p), WB
Order details Cat. No. ABIN4620453
$792.00
0.1 mg
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2856340
$466.18
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN563534
$305.71
50 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN2564445
$363.06
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application IF/ICC, WB
Order details Cat. No. ABIN6004320
$379.88
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF/ICC, WB
Order details Cat. No. ABIN2969213
$422.09
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN948659
$425.71
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN544819
$431.43
400 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF, WB
Order details Cat. No. ABIN6570434
$438.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityHuman
Application IC, IF, WB
Order details Cat. No. ABIN2966587
$487.50
200 μL
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application IHC, ELISA, WB
Order details Cat. No. ABIN2148673
$483.57
50 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF, WB
Order details Cat. No. ABIN6718204
$390.55
100 μL
Plus shipping costs $45.00
Delivery in 6 to 11 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN6264111
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN1874079
$471.34
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, IP, WB
Order details Cat. No. ABIN5971318
$506.51
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Order details Cat. No. ABIN5775964
$611.54
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN5671763
$289.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN5515029
$289.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN5515028
$289.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
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Pyruvate Dehydrogenase Complex, Component X (PDHX) Antigen Profile

Protein Summary

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit\; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with PDHX

  • pyruvate dehydrogenase complex, component X (pdhx) antibody
  • pyruvate dehydrogenase complex component X (PDHX) antibody
  • pyruvate dehydrogenase complex component X L homeolog (pdhx.L) antibody
  • E3-binding protein (pdhX) antibody
  • pyruvate dehydrogenase complex component X (pdhx) antibody
  • pyruvate dehydrogenase complex, component X (Pdhx) antibody
  • Ac1164 antibody
  • AI481367 antibody
  • DDBDRAFT_0168431 antibody
  • DDBDRAFT_0230192 antibody
  • DDB_0168431 antibody
  • DDB_0230192 antibody
  • DLDBP antibody
  • E3bp antibody
  • MGC86218 antibody
  • OPDX antibody
  • PDHX antibody
  • Pdx1 antibody
  • proX antibody
  • zgc:66110 antibody
  • zgc:85977 antibody

Protein level used designations for PDHX

pyruvate dehydrogenase complex, component X , pyruvate dehydrogenase protein X component, mitochondrial-like , dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex , lipoyl-containing pyruvate dehydrogenase complex component X , pyruvate dehydrogenase complex, E3-binding protein subunit , pyruvate dehydrogenase complex, lipoyl-containing component X , pyruvate dehydrogenase protein X component, mitochondrial , dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX) , E3-binding protein , E3BP , proX , pyruvate dehydrogenase protein X component

GENE ID SPECIES
393532 Danio rerio
423154 Gallus gallus
447247 Xenopus laevis
451120 Pan troglodytes
8618072 Dictyostelium discoideum AX4
100059260 Equus caballus
100220979 Taeniopygia guttata
100349815 Oryctolagus cuniculus
100379696 Xenopus (Silurana) tropicalis
100455315 Pongo abelii
100475970 Ailuropoda melanoleuca
100544023 Meleagris gallopavo
100586539 Nomascus leucogenys
8050 Homo sapiens
27402 Mus musculus
311254 Rattus norvegicus
475942 Canis lupus familiaris
517402 Bos taurus
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