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anti-Pyruvate Dehydrogenase Complex, Component X Antibodies

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A.

39 results:

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 220-468) antibody Primary Antibody

PDHX Reactivity: Human ICC, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5014241
$245.00
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 222-471) antibody Primary Antibody

PDHX Reactivity: Mouse ICC, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5014240
$252.00
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 1-501) antibody Primary Antibody

PDHX Reactivity: Human IF, WB Host: Mouse Polyclonal unconjugated
Catalog No. ABIN521742
$440.00
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 1-501) antibody Primary Antibody

PDHX Reactivity: Human IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN948658
$425.71
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) antibody Primary Antibody

PDHX Reactivity: Human, Mouse EIA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4620452
$892.80
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (C-Term) antibody Primary Antibody

PDHX Reactivity: Human, Mouse EIA, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4620453
$892.80
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (C-Term) antibody Primary Antibody

PDHX Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN185389
$481.84
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 6 to 7 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) antibody Primary Antibody

PDHX Reactivity: Human IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6145384
$589.88
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 13 to 14 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 1-109) antibody Primary Antibody

PDHX Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated
Catalog No. ABIN563534
$305.71
Plus shipping costs $45.00
50 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) (full length) antibody Primary Antibody

PDHX Reactivity: Human IF/ICC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6004320
$391.65
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 18 Business Days
  • Type Primary
    • Primary
  • Target Pyruvate Dehydrogenase Complex, Component X (PDHX)
    • Pyruvate Dehydrogenase Complex, Component X (PDHX)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Tumor Necrosis Factor alpha (TNF)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • Nuclear Factor-KB P65 (NFkBP65)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD44
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD19 Molecule (CD19)
    • CD8a Molecule (CD8A)
    • Hemagglutinin (HA)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Myc Proto-Oncogene protein (MYC)
    • Integrin alpha M (ITGAM)
    • CD8
    • Histone H4
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • Jun Proto-Oncogene (JUN)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • CD5 Molecule (CD5)
    • Interleukin 2 (IL2)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Synuclein, alpha (SNCA)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • CD14
    • Androgen Receptor (AR)
    • Mucin 1, Cell Surface Associated (MUC1)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • CD34
    • Cyclin-Dependent Kinase 1 (CDK1)
    • Activating Transcription Factor 2 (ATF2)
  • Application
    • Western Blotting (WB)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Enzyme Immunoassay (EIA)
    • Immunocytochemistry (ICC)
    • Immunoprecipitation (IP)
    • Flow Cytometry (FACS)
    • Immunochromatography (IC)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Images available
  • Host
    • Rabbit
    • Mouse
    • Goat
    • Sheep
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • AT1E11
  • Binding Specificity
    • C-Term
    • AA 1-501
    • AA 1-109
    • AA 1-300
    • AA 220-468
    • AA 222-471
    • AA 387-501
    • AA 429-459
    • Middle Region
    • Thr11
    • full length
  • Conjugate
    • Un-conjugated
    • Alexa Fluor 750
    • Biotin
    • Alexa Fluor 350
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • FITC
    • HRP
  • Isotype
    • IgG
    • Ig Fraction
  • Format
    • Liquid
    • Lyophilized

Pyruvate Dehydrogenase Complex, Component X (PDHX) Antigen Profile

Protein Summary

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit\; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with PDHX

  • pyruvate dehydrogenase complex, component X (pdhx) antibody
  • pyruvate dehydrogenase complex component X (PDHX) antibody
  • pyruvate dehydrogenase complex component X L homeolog (pdhx.L) antibody
  • E3-binding protein (pdhX) antibody
  • pyruvate dehydrogenase complex component X (pdhx) antibody
  • pyruvate dehydrogenase complex, component X (Pdhx) antibody
  • Ac1164 antibody
  • AI481367 antibody
  • DDBDRAFT_0168431 antibody
  • DDBDRAFT_0230192 antibody
  • DDB_0168431 antibody
  • DDB_0230192 antibody
  • DLDBP antibody
  • E3bp antibody
  • MGC86218 antibody
  • OPDX antibody
  • PDHX antibody
  • Pdx1 antibody
  • proX antibody
  • zgc:66110 antibody
  • zgc:85977 antibody

Protein level used designations for PDHX

pyruvate dehydrogenase complex, component X , pyruvate dehydrogenase protein X component, mitochondrial-like , dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex , lipoyl-containing pyruvate dehydrogenase complex component X , pyruvate dehydrogenase complex, E3-binding protein subunit , pyruvate dehydrogenase complex, lipoyl-containing component X , pyruvate dehydrogenase protein X component, mitochondrial , dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX) , E3-binding protein , E3BP , proX , pyruvate dehydrogenase protein X component

GENE ID SPECIES
393532 Danio rerio
423154 Gallus gallus
447247 Xenopus laevis
451120 Pan troglodytes
8618072 Dictyostelium discoideum AX4
100059260 Equus caballus
100220979 Taeniopygia guttata
100349815 Oryctolagus cuniculus
100379696 Xenopus (Silurana) tropicalis
100455315 Pongo abelii
100475970 Ailuropoda melanoleuca
100544023 Meleagris gallopavo
100586539 Nomascus leucogenys
8050 Homo sapiens
27402 Mus musculus
311254 Rattus norvegicus
475942 Canis lupus familiaris
517402 Bos taurus

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