Pyruvate Dehydrogenase Phosphatase Proteins

Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex.

Data Quality
  • 6
Type
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    Protein
Antigen
  • 9
Reactivity
  • 5
  • 2
  • 1
  • 1
Application
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  • 5
  • 2
  • 2
Host
  • 5
  • 2
  • 2
Binding Specificity
  • 3
  • 1
  • 1
  • 1
Conjugate
  • 2
  • 4
  • 2
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Protein Type
  • 9
Format
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9 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3085625
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3122191
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN2126596
$697.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3011412
$703.49
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2728598
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2728599
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
ReactivityMouse (Murine)
Application SDS, WB
Order details Cat. No. ABIN6382393
$1,744.65
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityRat (Rattus)
Application ELISA
Order details Cat. No. ABIN1593562
$3,314.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1664045
$3,314.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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Pyruvate Dehydrogenase Phosphatase (PDP) Protein Profile

Protein Summary

Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported\; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with PDP

  • Pyruvate dehydrogenase phosphatase (Pdp) antibody
  • pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial (LOC413080) antibody
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1) antibody
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (Pdp1) antibody
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (pdp1) antibody
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog (pdp1.L) antibody
  • 153332_at antibody
  • CG12151 antibody
  • Dmel\\CG12151 antibody
  • Gm1024 antibody
  • im:7157162 antibody
  • PDH antibody
  • pdp antibody
  • pdp1 antibody
  • PDPC antibody
  • ppm2c antibody
  • zgc:174908 antibody

Protein level used designations for PDP

CG12151-PA , CG12151-PB , Pdp-PA , Pdp-PB , pyruvate dehydrogenase phosphatase , PDP 1 , PDPC 1 , [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial , protein phosphatase 2C, magnesium-dependent, catalytic subunit , pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase , pyruvate dehydrogenase phosphatase catalytic subunit 1 , protein phosphatase 2C, magnesium dependent, catalytic subunit , pyruvate dehydrogenase phosphatase isoenzyme 2 , pyruvate dehydrogenase phosphatase isoenzyme 1 , pyruvate dehydrogenase phosphatase, catalytic subunit 1 , pyruvate dehyrogenase phosphatase catalytic subunit 1 , pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog

GENE ID SPECIES
31683 Drosophila melanogaster
413080 Apis mellifera
54704 Homo sapiens
381511 Mus musculus
54705 Rattus norvegicus
280891 Bos taurus
100153002 Sus scrofa
477941 Canis lupus familiaris
558728 Danio rerio
447514 Xenopus laevis
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