RAS (RAD and GEM)-Like GTP Binding 2 Proteins (REM2)

a Ras-related small GTP-binding protein that is found in high levels in neuronal tissues [RGD, Feb 2006].. Additionally we are shipping REM2 Antibodies (15) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
REM2 140743 Q8VEL9
REM2 64626 Q9WTY2
REM2 161253 Q8IYK8
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top REM2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,227.64
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,227.64
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$2,924.17
Details

REM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human ,
,

More Proteins for RAS (RAD and GEM)-Like GTP Binding 2 (REM2) Interaction Partners

Mouse (Murine) RAS (RAD and GEM)-Like GTP Binding 2 (REM2) interaction partners

  1. Rem2 stabilizes intrinsic excitability and spontaneous firing in visual circuits.

  2. report that substitution of two key amino acid residues in the Rem2 N terminus (Arg-79 and Arg-80) completely abolishes its ability to inhibit CaMKII

  3. Our results highlight Rem2 as a unique molecule that transduces changes in neuronal activity detected at the cell membrane to morphologically relevant changes in gene expression in the nucleus

  4. Study have shown that Rem2 is expressed in a variety of nervous system tissues, but is enriched in the basal ganglia. The function of Rem2 in the basal ganglia is unknown, but may be important for neuronal maturation during development, and/or neuroplasticity in adulthood.

  5. Nuclear localization of RGK proteins (Rad, Rem, and Rem2) contributes to the suppression of RGK-mediated cell shape remodeling.

  6. Voltage dependant calcium channels blockade by Rem2 is likely to be controlled by both the localized concentration of membrane phosphorylated phosphatidylinositide lipids and direct 14-3-3 binding to the Rem2 C-terminus.

Human RAS (RAD and GEM)-Like GTP Binding 2 (REM2) interaction partners

  1. 2 novel gene variants in REM2 and KCNK17 that provide a physiologically plausible explanation for variable expressivity in a large subset of patients in a multigenerational long QT syndrome type 2 family

  2. report that substitution of two key amino acid residues in the Rem2 N terminus (Arg-79 and Arg-80) completely abolishes its ability to inhibit CaMKII

  3. conclude that endogenous Rem2 is a positive regulator of functional, excitatory synapse development and a negative regulator of dendritic complexity

  4. Rem2 has a role in neuronal plasticity hrough co-trafficking with CaMKIIa

  5. molecular mechanisms by which Rem2 knockdown affected synaptogenesis and Ca(2) homeostasis in cultured rat hippocampal neurons

  6. our results suggest that Rem2 regulates dendritic branching and synapse development

  7. Rem2 mediates the fibroblastic growth factor 2 (FGF2) signaling pathway to maintain proliferation of hESCsby suppressing the transcriptional activity of p53 and cyclin D(1)

  8. inhibition of L-type Ca2+ channels by Rem2 signaling may represent a new and potentially important mechanism for regulating Ca2+-triggered exocytosis in hormone-secreting cells, including insulin secretion in pancreatic beta-cells

  9. data unravel a possible molecular mechanism for Rem2-induced angiogenesis and suggests Rem2 as a potential novel target for treating pathological angiogenesis

REM2 Protein Profile

Protein Summary

a Ras-related small GTP-binding protein that is found in high levels in neuronal tissues

Gene names and symbols associated with REM2

  • RRAD and GEM like GTPase 2 (REM2)
  • rad and gem related GTP binding protein 2 (Rem2)
  • RRAD and GEM like GTPase 2 (Rem2)
  • AW411893 protein

Protein level used designations for REM2

RAS (RAD and GEM)-like GTP binding 2 , GTP-binding protein REM 2 , rad and Gem-like GTP-binding protein 2 , GEM, REM, Kir family small G-protein , GTP-binding protein REM2 , Ras-related GTP-binding protein of the Rad/Gem/Kir family member 2 , Ras-related GTP-binding protein of the Rad/Gem/Kir family, member 2 , rad and gem related GTP binding protein 2 , Rad and Gem-related 2 (rat homolog)

GENE ID SPECIES
467399 Pan troglodytes
490603 Canis lupus familiaris
531597 Bos taurus
140743 Mus musculus
64626 Rattus norvegicus
161253 Homo sapiens
Selected quality suppliers for REM2 Proteins (REM2)
Did you look for something else?