anti-Rab11 Family-Interacting Protein 1 (RAB11FIP1) Antibodies

Human Rab11 Family-Interacting Protein 1 (RAB11FIP1) interaction partners

1. The findings thus define that delivery of recycling cargo toward the ERC requires spatial and sequential coupling of Rab11 activity with PtdIns(3)P turnover.

2. Phosphorylation of RCP at Ser(435) by Lemur tyrosine kinase-3 (LMTK3) and of EphA2 at Ser(897) by Akt are both necessary to promote Rab14-dependent (and Rab11-independent) trafficking of EphA2 which generates cell:cell repulsion events that drive tumour cells apart.

3. The article focuses on the latest advances regarding the mechanisms that ensure the compartmentalized regulation of Rab11 function through its interaction with phosphoinositides. (Review)

4. High RCP expression is associated with lung metastasis in ovarian cancer.

5. our findings indicate that FIP1C acts as a tumor suppressor in the context of ErbB2-positive breast cancer

6. Findings suggest that overexpression of micro ribonucleic acid-93 (miR-93) via targeting RAB11 family interacting protein (RAB11FIP1) as an early event plays an important role in oncogenesis of cervical cancer. MiR-93 and its target protein RAB11FIP1 may be potential therapeutic targets for cervical cancer and its precursors.

7. REI/SH3BP5 protein family is conserved in evolution and is a group of new guanine nucleotide exchange factors for Rab11.

8. Rab11-FIP1A associates with and regulates trafficking at an early step in the process of membrane recycling

9. GTPase Rab11, but not Rab4, is involved in the recycling of hERG channels.

10. We find that Rab14 indeed binds to RCP, albeit with reduced affinity relative to conventional Rab11-FIP and Rab25-FIP complexes. However, in vivo, Rab11 recruits RCP onto biological membranes.

11. rab11 effector protein FIP1 regulates adiponectin trafficking and secretion

12. Mitochondrial remodeling was associated with increased proximity between Rab11a and mitochondrial membranes, changes in fusion-fission dynamics, and mitochondrial relocalization of the Drp1, which was regulated by the Rab11a effector protein FIP1/RCP.

13. findings support a model for HIV-1 Env incorporation in which specific targeting to the particle assembly microdomain on the plasma membrane is mediated by FIP1C and Rab14

14. These findings suggest that Rab11-FIP1 proteins participate in spatially and temporally distinct steps of the recycling process along a complex and dynamic tubular network in which Rab11-FIPs occupy discrete domains

15. Rab11 is differentially phosphorylated by distinct PKC isoenzymes; this post-translational modification might be a regulatory mechanism of intracellular trafficking.

16. results suggest that Rab5 is involved in CB2 endocytosis and that internalized receptors are recycled via a Rab11 associated pathway rather than the rapid Rab4 associated pathway.

17. FIP1/RCP binding to Golgin-97 is required for tethering and fusion of recycling endosome-derived retrograde transport vesicles to the trans-Golgi network.

18. An interaction with Rab11 is necessary for long-range targeting of beta1 integrins to the growth cone along axons and in neurons.

19. Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein

20. Receptor cell surface expression and endocytosis experiments reveal that the small GTPase Rab11 protein is a determinant factor in controlling thromboxane A2 receptor beta isoform recycling back to the cell surface.