-
Serum levels of PCT and PSP are promising biomarkers for early diagnosis of pediatric acute osteomyelitis.
-
PSP/reg levels are significantly up-regulated in diabetic kidney disease patients and might be related to renal injury
-
Both univariate and multivariate analysis demonstrated that REG1A expression was associated with OS and PFS, and conducted harmful effects on nasopharyngeal carcinoma progression and survival. This study suggested that REG1A expression could serve as an independent adverse factor for survival in nasopharyngeal carcinoma.
-
Reg I may play a role in the maintenance of mucosal barrier function by inducing tight junction proteins such as claudins 3 and 4.
-
the prognostic value of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), and pancreatic stone protein (PSP) in children with sepsis, was investigated.
-
REG1alpha was overexpressed in bladder cancer tissues compared with adjacent normal samples. Downregulation of REG1alpha expression in urothelial bladder cancer can reduce tumor growth, migration, invasion and angiogenesis.
-
REG-I is expressed in head and neck squamous cell carcinoma and is associated with a longer survival status.
-
We have established a novel, three-protein biomarker panel that is able to detect patients with early-stage pancreatic cancer in urine specimens:LYVE-1, REG1A, and TFF1 were selected as candidate biomarkers
-
post-operative serum PSP levels were significantly associated with the presence of infection in both the on-pump and off-pump setting.
-
REG Ialpha protein may play a role in angiogenesis during progression of gastric cancer
-
PSP/reg is significantly up-regulated in T2DM patients, and PSP/reg levels are related to the duration of diabetes.
-
the expression of REG Ialpha and REG Ibeta may be upregulated in human beta cells under inflammatory conditions through the JAK/STAT pathway
-
Collectively, these findings suggest that REG Ialpha activates c-Jun via the JNK and ERK pathway, thereby enhancing radiosensitivity
-
Pancreactic stone protein levels were able to diagnose sepsis in patients admitted to intensive care units.
-
PSP/reg levels were significantly higher in patients with a PELOD score of 12 or higher or in those with multiple organ dysfunction syndrome. Patients who died tended to have higher PSP/reg levels.
-
REG Ialpha overexpression is a characteristic ofsessile serrated adenoma/polyps of the colon, which appears to reflect aberration of crypt cell compartmentalization.
-
The effects of REG IA on AD and SCC cells were different in the in vitro study, and a correlation between REG IA expression and patient prognosis was noted in the in vivo study
-
Reduced REG1A expression is associated with chemosensitivity in advanced thoracic esophageal squamous cell carcinoma.
-
PSP/reg and CRP are differentially regulated by HNF1A and HNF4A in maturity-onset diabetes of the young
-
Immunohistochemistry against known cell-type markers on serial sections has localised the expression of REGs to metaplastic Paneth cells (REG1A, REG1B and REG3A) and enteroendocrine cells (REG4), with a marked expansion of expression during inflammation.
