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REG1B is a type I subclass member of the Reg gene family. Additionally we are shipping REG1B Antibodies (39) and REG1B Kits (24) and many more products for this protein.
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REG (show EXTL3 Proteins)-I is expressed in head and neck squamous cell carcinoma and is associated with a longer survival status.
the expression of REG (show EXTL3 Proteins) Ialpha and REG (show EXTL3 Proteins) Ibeta may be upregulated in human beta cells under inflammatory conditions through the JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) pathway
Additional serum biomarkers, particularly SYCN (show SYCN Proteins) and REG1B, when combined with CA19.9, show promise as improved diagnostic indicators of pancreatic cancer, which therefore warrants further validation.
Immunohistochemistry against known cell-type markers on serial sections has localised the expression of REGs to metaplastic Paneth cells (REG1A (show REG1A Proteins), REG1B and REG3A (show REG3A Proteins)) and enteroendocrine cells (REG4 (show REG4 Proteins)), with a marked expansion of expression during inflammation.
Higher REG1B stool concentrations at month 3 were significantly and independently associated with a growth shortfall in Bangladeshi and Peruvian children.
REG (show EXTL3 Proteins) 1A and REG (show EXTL3 Proteins) 1B were upregulated during amebiasis and may function to protect the intestinal epithelium from parasite-induced apoptosis.
The expression of MK-1 (show KCNA1 Proteins) and/or RegIV (show REG4 Proteins) might be closely related to the carcinogenesis, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma
This finding suggests that REG (show EXTL3 Proteins) I may act through IL-6 (show IL6 Proteins) to exert effects on squamous esophageal cancer cell biology.
did not find any association between abnormalities of either reg1 alpha or reg1 beta gene with type 1 diabetes mellitus, fibrocalculous pancreatopathy, or type 2 diabetes mellitus
This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
, lithostathine 1 beta
, pancreatic stone protein 2
, regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein)
, regenerating islet-derived protein 1-beta
, regenerating protein I beta
, secretory pancreatic stone protein 2