Regulator of Calcineurin 2 Proteins (RCAN2)

RCAN2 encodes a member of the regulator of calcineurin (RCAN) protein family. Additionally we are shipping RCAN2 Antibodies (54) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RCAN2 10231 Q14206
RCAN2 53901 Q9JHG2
Rat RCAN2 RCAN2 140666 Q8CH27
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Top RCAN2 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Mouse His tag 0.05 mg Log in to see 2 to 3 Days
$295.63
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$400.00
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Yeast Cynomolgus His tag   1 mg Log in to see 60 to 71 Days
$2,476.83
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,476.83
Details
Yeast Chimpanzee His tag   1 mg Log in to see 60 to 71 Days
$2,476.83
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Yeast Yeast His tag   1 mg Log in to see 60 to 71 Days
$2,687.67
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Yeast Please inquire His tag   1 mg Log in to see 60 to 71 Days
$2,476.83
Details

RCAN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) ,

More Proteins for Regulator of Calcineurin 2 (RCAN2) Interaction Partners

Human Regulator of Calcineurin 2 (RCAN2) interaction partners

  1. RCAN2 expression is upregulated in human masticatory mucosa during wound healing

  2. our data have elucidated the molecular and cellular mechanism whereby PGF (show PGF Proteins)(2alpha) regulates CXCL8 (show IL8 Proteins) expression via the FP receptor (show PTGFR Proteins) in endometrial adenocarcinomas and have highlighted RCAN1 (show RCAN1 Proteins)-4 as a negative regulator of CXCL8 (show IL8 Proteins) expression

  3. the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin.

  4. DSCR1 (show RCAN1 Proteins)-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 (show RCAN1 Proteins) in inhibiting calcineurin activity and restraining VEGF (show VEGFA Proteins)-mediated angiogenesis.

Mouse (Murine) Regulator of Calcineurin 2 (RCAN2) interaction partners

  1. RCANs play critical roles in bone homeostasis by regulating both osteoclastogenesis and osteoblastogenesis, and they serve as inhibitors for calcineurin-NFATc1 (show NFATC1 Proteins) signaling both in vivo and in vitro.

  2. our results indicate that Rcan2 and estradiol might regulate body weight through different mechanisms in female mice. Rcan2 increases food intake and promotes weight gain, while estradiol increases energy expenditure possibly by regulating physical activity.

  3. Rcan2 and Rps6kb1 (show RPS6KB1 Proteins) mutations both affect growth and body weight of mice, though likely through different mechanisms

  4. Rcan2 regulates osteoblast function and its expression in bone is regulated by thyroid status in vivo

  5. an Rcan2-dependent mechanism which regulates food intake and promotes weight gain through a leptin (show LEP Proteins)-independent pathway

  6. Genetic inhibition of calcineurin in Zaki-4 transgenic mice induces diastolic dysfunction in mice with chronic pressure overload.

RCAN2 Protein Profile

Protein Summary

This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with RCAN2

  • regulator of calcineurin 2 (rcan2)
  • regulator of calcineurin 2 (RCAN2)
  • regulator of calcineurin 2 (Rcan2)
  • Csp2 protein
  • Dcip2 protein
  • DKFZp459H071 protein
  • Dscr1l1 protein
  • MCIP2 protein
  • rcan2 protein
  • RCN2 protein
  • si:ch211-124g24.1 protein
  • Zaki-4 protein
  • ZAKI4 protein
  • zgc:85746 protein

Protein level used designations for RCAN2

regulator of calcineurin 2 , calcipressin-2 , Down syndrome critical region gene 1-like 1 , Calcipressin-2 , Down syndrome candidate region 1-like 1 , myocyte-enriched calcineurin-interacting protein 2 , thyroid hormone-responsive (skin fibroblasts) , thyroid hormone-responsive protein ZAKI-4 , calcineurin inhibitory protein ZAKI-4 , down syndrome candidate region 1-like protein 1 , myocyte-enriched calcineurin interactin protein 2 , Down syndrome critical region gene1-like 1 , Down syndrome critical region gene 1-like 1 protein , down syndrome candidate region 1-like 1

GENE ID SPECIES
496648 Xenopus (Silurana) tropicalis
407988 Danio rerio
100171807 Pongo abelii
100306775 Salmo salar
10231 Homo sapiens
53901 Mus musculus
140666 Rattus norvegicus
422057 Gallus gallus
609864 Canis lupus familiaris
525636 Bos taurus
462742 Pan troglodytes
Selected quality suppliers for RCAN2 Proteins (RCAN2)
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