anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) Antibodies

RFX1 is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. Additionally we are shipping Regulatory Factor X, 1 (Influences HLA Class II Expression) Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RFX1 5989 P22670
RFX1 19724 P48377
RFX1 288906  
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Top anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RFX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate RFX1 is supported by BioGPS gene expression data to be expressed in HEK293T WB Suggested Anti-RFX1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control:.93T cell lysate  RFX1 is supported by BioGPS gene expression data to be expressed in HEK293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RFX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Rfx1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: Mouse Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RFX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  MCF7 cell lysate Host:  Mouse  Target Name:  RFX1  Sample Tissue:  Mouse Pancreas  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: RFX1 Antibody [NBP1-52654] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-RFX1 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 6 mcg/mg lysate. RFX1 was also immunoprecipitated by rabbit anti-RFX1 antibodies NBP1-52652 and NBP1-52653, which recognize upstream epitopes. Immunohistochemistry-Paraffin: RFX1 Antibody [NBP1-52654] - IHC-P detection of mouse RFX1 in FFPE section of murine renal cell carcinoma. Primary antibody used at a dilution of 1:1000. 0.1 mL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated IF, WB Fluorescent image of U251 cell stained with RFX1 Antibody (C-term).U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with RFX1 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃).RFX1 immunoreactivity is localized to Nucleus significantly. RFX1 Antibody (C-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the RFX1 antibody detected the RFX1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB   0.4 mL Log in to see 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB Western Blot: RFX1 Antibody [NBP2-20142] - Sample (30 ug of whole cell lysate) A: NT2D1 5% SDS PAGE gel, diluted at 1:500. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details

Top referenced anti-Regulatory Factor X, 1 (Influences HLA Class II Expression) Antibodies

  1. Human Polyclonal RFX1 Primary Antibody for ICC, IF - ABIN4350269 : Zhu, Li, Yang, Tian, Wang, Yuan, Dong, He, Wang, Li: Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation. in Scientific reports 2016 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Regulatory Factor X, 1 (Influences HLA Class II Expression) Interaction Partners

Human Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) interaction partners

  1. RFX1 interacts with the D sequence of adeno-associated virus inverted terminal repeat and regulates AAV transduction.

  2. RFX1 expression was significantly lower in HCC tissues compared to the corresponding non-tumor tissues. In vitro studies suggested that knocking down RFX1 facilitated HCC cell invasion, while overexpression of RFX1 reduced the invasion of HCC cells. RFX1 regulated expression of some epithelial-mesenchymal transition markers.

  3. Findings indicate that RFX1 functions downstream of STAT3 and phosphorylated STAT3 can inhibit RFX1 expression and suggest a unique role for RFX1 in Th17-related autoimmune diseases.

  4. Results show that reduced miRNA-124 improved microglia activation and up-regulated its downstream target RFX1, indicating that RFX1, as one of the target transcripts, facilitates microglial activation by miR-124 regulation; identified the binding site through which RFX1 directly regulates ApoE, may explain the missing link between decreased miRNA-124 and ineffective Abeta uptaking during aging.

  5. induction of ciliogenesis increases the expression of RFX and dyslexia candidate genes

  6. Data show that transcription factor regulatory factor X 1 (RFX1) protein expression can be tightly regulated by polyubiquitination-mediated proteosomal degradation via STIP1 homology and U-box containing protein 1 (STUB1).

  7. therapeutic targets for childhood severe asthmatics identified thru DNA microarray

  8. Data indicate that regulatory factor X transcription factor RFX-1 regulates SC-2001-mediated SHP-1 Phosphatase transcription in hepatocellular carcinoma cells.

  9. regulatory factor 1 directly regulates CD44 expression in glioblastoma

  10. Taken together, this study suggests ciliogenic RFX transcription factors regulate FGF-1B promoter activity and the maintenance of F1BGFP(+) NSPCs and GBM-SCs.

  11. RFX1 reduces cell proliferation through inhibiting the TGFbeta2-ERK signaling pathway. RFX1 blocks TGFbeta2 expression through its direct action on TGFbeta2 transcription.

  12. NLRC5-mediated histocompatibiility class I gene induction requires the W/S and X1, X2 cis-regulatory elements.

  13. in serum- or IGF-1-stimulated breast cancer MCF-7 cells, JNK induces SHP1 expression through the binding of AP-4 and RFX-1 transcription factors to the epithelial tissue-specific SHP1 promoter.

  14. RFX1 recruits SUV39H1 to the promoter regions of the CD11a and CD70 genes in CD4(+) T cells, thereby regulating local H3K9 tri-methylation levels.

  15. regulates autoimmunity via epigenetic modifications in T cells of systemic lupus erythematosus patients

  16. We show binding of RFX proteins to an evolutionarily conserved X-box in the ALMS1 proximal promoter and present evidence that these proteins are responsible for ALMS1 transc

  17. RFX1 may negatively regulate the self-renewal of GBM-SCs through modulating FGF-1B and FGF1 expression levels by binding the 18-bp cis-elements of the F1B promoter.

  18. Data show that two regulatory factor for X box (RFX1 and 3) binding sites in exon1 of both the mouse and human microtubule-associated protein (MAP1A) gene are important for effective transcriptional repression in non-neuronal cells.

  19. Disruption of the RFX site within 263P blunts repressor activity in transfected GC cells; however, repression is only abolished when both PSE-A/RFX and PSE-B/NF-1 sites are mutated.

  20. novel role for the RFX family of transcription factors as modulators of Ras signalling in epithelial cells

Mouse (Murine) Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) interaction partners

  1. RFX1 transcriptionally targets Itga6 in Sertoli cells, thereby, helping maintain the integrity of the basal lamina during testis cord development.

  2. Results show that reduced miRNA-124 improved microglia activation and up-regulated its downstream target RFX1, indicating that RFX1, as one of the target transcripts, facilitates microglial activation by miR-124 regulation; identified the binding site through which RFX1 directly regulates ApoE, may explain the missing link between decreased miRNA-124 and ineffective Abeta uptaking during aging.

  3. This study suggests that ciliogenic Rfx transcription factors regulate Msi1 expression in neural stem/progenitor cells.

  4. regulatory factor 1 directly regulates CD44 expression in glioblastoma

  5. RFX1 may have negative effect on cell proliferation of Sertoli cells via modulating Spata4 expression levels by binding the conserved 14-bp cis-elements of Spata4 promoter.

  6. Rfx1 could be an indicator of progression from Barrett's esophagus to adenocarcinoma.

  7. These results suggest a significant expression of RFX1 proteins in the mammalian brain.

  8. RFX1 may negatively regulate the self-renewal of GBM-SCs through modulating FGF-1B and FGF1 expression levels by binding the 18-bp cis-elements of the F1B promoter.

  9. RFX1 may play roles in haploid cells during mouse spermatogenesis

  10. RFX1 mediates the immediate early response of the Id2 gene by serum stimulation and suggest that the function of RFX1 is regulated intramolecularly in its suppression in growth-arrested cells.

  11. RFX1 regulates expression of genes that are essential for early embryonic development/survival and that RFX1 function can not be compensated by other RFX1 family members.

Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1) Antigen Profile

Protein Summary

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.

Gene names and symbols associated with RFX1

  • regulatory factor X1 (RFX1) antibody
  • regulatory factor X, 1 (influences HLA class II expression) (Rfx1) antibody
  • regulatory factor X1 (Rfx1) antibody
  • regulatory factor X, 1a (influences HLA class II expression) (rfx1a) antibody
  • AI047719 antibody
  • AI385641 antibody
  • EFC antibody
  • RFX antibody
  • zgc:162914 antibody

Protein level used designations for RFX1

MHC class II regulatory factor RFX , MHC class II regulatory factor RFX1 , enhancer factor C , regulatory factor X 1 , trans-acting regulatory factor 1 , transcription factor RFX1 , vregulatory factor X, 1 (influences HLA class II expression) , regulatory factor X1

GENE ID SPECIES
5989 Homo sapiens
19724 Mus musculus
288906 Rattus norvegicus
484908 Canis lupus familiaris
789747 Bos taurus
100736012 Cavia porcellus
100038773 Danio rerio
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