Reticulocalbin 1, EF-Hand Calcium Binding Domain Proteins (RCN1)

Mouse (Murine) Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1) interaction partners

1. In the adult mice, RCAN1 (show RCAN1 Proteins) was mainly expressed in the neuropil throughout the brain.

Human Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1) interaction partners

1. RCN1 (show RCAN1 Proteins) may promote cell survival and serve as a useful target for cancer therapy.

2. irradiated tumor cells were observed to significantly up-regulate the expression of calcium-binding proteins CALM1, CALU (show CALU Proteins), and RCN1 (show RCAN1 Proteins), suggesting important roles for these mediators in promoting tumor cell survival during hypoxia

3. RCN1 (show RCAN1 Proteins) expression was not statistically significantly different to healthy controls but was associated with disease activity score and could be used as a stratification biomarker for systemic sclerosis patients.

4. reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance

5. Ca(2 (show CA2 Proteins)+) binding caused an increase in the alpha-helix content of human RCN1 (show RCAN1 Proteins). On the other hand, RCN1 (show RCAN1 Proteins) did not change the structure with Mg.

6. a promising role of RCN1 (show RCAN1 Proteins) as a possible marker in Renal cell carcinoma (show MOK Proteins)

7. reticulocalbin-1 may be an important molecule in understanding lymphatic endothelial cells in tumors function and control of lymphatic metastasis.

8. Increased RCN1 (show RCAN1 Proteins) is associated with systemic sclerosis and nephrogenic systemic fibrosis.

9. deletion of Rcn1 (show RCAN1 Proteins) directly or indirectly contributes to the eye phenotype in Pax6 (show PAX6 Proteins) contiguous gene deletions

10. RCN1 (show RCAN1 Proteins) also is expressed on the cell surface of several endothelial cell lines, including human dermal microvascular endothelial cells (HDMVECs), bone marrow endothelial cells (BMEC), and transformed human bone marrow endothelial cells (TrHBMEC).