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RTN3 belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. Additionally we are shipping Reticulon 3 Antibodies (50) and and many more products for this protein.
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This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
ASY interacting protein
, NSP-like protein 2
, NSP-like protein II
, homolog of ASY protein
, neuroendocrine-specific protein-like 2
, neuroendocrine-specific protein-like II
, Nsp-like II
, reticulon 3
, reticulon protein 3