anti-Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) Antibodies

The protein encoded by RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. Additionally we are shipping RECK Kits (10) and RECK Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RECK 8434 O95980
RECK 53614 Q9Z0J1
RECK 313488  
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Top anti-RECK Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Reck Antibody Titration: 1.0 ug/ml Positive Control: Mouse Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using RECK Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using RECK Antibody. The picture on the right is treated with the synthesized peptide. 100 μL Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of k562 cells using RECK / ST15  Antibody  (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human brain tissue reacted with RECK / ST15  Antibody  which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of RECK using Jurkat whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of RECK Antibody (Center) (ABIN653207) in HepG2 cell line lysates (35 µg/lane). RECK (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with RECK Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of RECK using anti-RECK antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human placenta tissue lysates.After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-RECK antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for RECK at approximately 106KD. The expected band size for RECK is at 106KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of RECK Antibody in HepG2 cell line lysates (35ug/lane) Formalin-fixed and paraffin-embedded human brain tissue reacted with RECK Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 16 Days
$476.15
Details

Top referenced anti-RECK Antibodies

  1. Human Polyclonal RECK Primary Antibody for IF (cc), IF (p) - ABIN681418 : Siddesha, Valente, Sakamuri, Gardner, Delafontaine, Noda, Chandrasekar: Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECK. in Journal of cellular physiology 2014 (PubMed)
    Show all 2 Pubmed References

More Antibodies against RECK Interaction Partners

Human Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) interaction partners

  1. Results report that the expression of RECK is significantly lower in cervical cancer cells than in normal cells. The relative protein expression levels of p53 signaling (p21 and Bax) were significantly elevated when RECK was upregulated, suggesting that the overexpression of RECK could promote the activation of p53 signaling pathway.

  2. overexpressed in trophoblasts from preeclampsia

  3. The expression of RECK was inhibited by the transfection of miR-96 mimics. RECK mRNA level was reduced by miR-96 mimics and increased by miR-96 inhibitor. In the invasion assay, miR-96 mimics were shown to promote tumor invasion.

  4. Results suggested that some paracrine substances produced by 786-0 cells may reduce RECK expression of adjacent HMEC-1 cells and enhance their proliferation and in vitro angiogenic capacity.

  5. RECK gene polymorphisms were closely associated with active proliferation, capsular invasion, and clinical recurrence of ameloblastoma.

  6. Collectively, these results demonstrated that IL-32alpha upregulates the atheroprotective genes Timp3 and Reck by downregulating microRNA-205 through regulation of the Rprd2-Dgcr8/Ddx5-Dicer1 biogenesis pathway.

  7. RECK CpG methylation pattern may predict prognosis and drug-sensitivity of breast cancers.

  8. The expression of RECK in human healthy and diseased gingiva may contribute to periodontal physiological and pathological processes; low RECK expression may be associated with the enhanced MMP-2 and MMP-9 production in inflamed gingiva.

  9. the RECK gene polymorphism influences molecular carcinogenesis and clinic pathological features of hepatocellular carcinoma within the Egyptian population

  10. Reversion-inducing, cysteine-rich protein with kazal motifs (RECK) was identified as the direct and functional target of miR-92b in osteosarcoma

  11. RECK expression in uterine leiomyoma is negatively regulated by miR-15b.

  12. RECK could regulate the expressions of MMP-2, 9 and MT1-MMP as a cell surface-signaling molecule. Authors propose that RECK may play an important role in regulating MMPs in the ECM degradation of periodontal diseases.

  13. Low expression of RECK is associated with oral cancer.

  14. RECK Gene Promoter rs10814325 Polymorphism is associated with metastasis in Hepatocellular Carcinoma

  15. the aim of this study was to analyze the effect of RECK gene rs 11788747 single nucleotide polymorphism (SNP) on hepatocellular carcinoma (HCC) susceptibility.

  16. Findings suggest that RECK transcript variants might have opposite roles in GBM biology and the ratio of their expression levels may be informative for the prognostic outcome of GBM patients.

  17. miR-21 has a role in upregulating PTEN, RECK and PDCD4 in glioma

  18. RECK is a regulator of hMSC functions suggesting that modulation of RECK may improve the development of hMSC-based therapeutical approaches in regenerative medicine.

  19. MMP-9/RECK imbalance in cervical smears is significantly associated with high-grade cervical diseases and infection by alpha-9 HPV and C. trachomatis.

  20. RECK is not an independent prognostic marker for breast cancer

Mouse (Murine) Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) interaction partners

  1. Reck was identified to be one of the target genes of miR-497-5p, and Reck could suppress the expression of matrix metalloproteinase-2 (Mmp2) and Mmp9, which could activate latent transforming growth factor-beta1 (TGF-beta1).

  2. experiments indicate that Reck and Gpr124 are part of the cell surface protein complex that transduces Wnt7a- and Wnt7b-specific signals in mammalian CNS Epithelial Cells to promote angiogenesis and regulate the BBB.

  3. These findings demonstrate the importance of appropriate cell-cell interactions and ECM maintenance for angiogenesis and the involvement of Reck as a critical regulator of these events.

  4. RECK-mediated beta1-Integrin regulation by TGF-beta1 is critical for wound contraction in mice.

  5. MiR-21 modulated the osteoporosis by targeting RECK.

  6. microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting RECK.

  7. The RECK silencing-EGFR-HIF-2alpha axis might be a key molecular mechanism to induce hyperplastic phenotype of epithelial cells.

  8. Angiotensin II suppresses RECK, but induces matrix metalloproteinases both in vivo and in vitro.

  9. therapeutic concentrations of ASA inhibited IL-18-induced H(2)O(2) generation, MMP9 activation, RECK suppression, and CF migration.

  10. these data suggest that RECK is a novel transcriptional target of FXR in mouse liver, and provide clues to better understanding the function of FXR in liver.

  11. RECK expression in the mouse uterus is steroidally regulated and within endometrial epithelial and stromal cells, RECK regulates MMP9, but not MMP2 activity.

  12. After treatment with NS398, RECK expression increased and MMP9 expression decreased in mice with prostate cancer.

  13. RECK is a novel modulator of EGFR signaling.

  14. It plays a role in CNS development as Notch signal regulator. (review)

  15. This study suggested that Reck in protection of ECM/tissue integrity and promotion of functional recovery in the brain after transient cerebral ischemia.

  16. Findings implicate Reck in vascular remodeling, possibly through non-sprouting angiogenesis, in both maternal and embyonic tissues.

  17. The expression of RECK was found to be temporally regulated, suggesting roles in palatal ontogeny; remodeling of the extracellular matrix is finely modulated during secondary palate development and occurs in a sequential manner.

  18. Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs.

  19. Reck expression was up-regulated at high cell density, low serum, or after treatment with some kinase inhibitors, such as PP2 (Src inhibitor), LY294002 (PI3-kinase inhibitor), and PF573228 (FAK inhibitor), in mouse embryo fibroblasts.

  20. Oncogenic ras represses RECK expression via a histone deacetylation mechanism.

RECK Antigen Profile

Protein Summary

The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.

Gene names and symbols associated with RECK

  • reversion inducing cysteine rich protein with kazal motifs (RECK) antibody
  • reversion-inducing-cysteine-rich protein with kazal motifs (Reck) antibody
  • mRECK antibody
  • St15 antibody

Protein level used designations for RECK

membrane-anchored glycoprotein (metastasis and invasion) , reversion-inducing cysteine-rich protein with Kazal motifs , suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs) , suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs) , suppressor of tumorigenicity 15 protein , Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK) , membrane-anchored glycoprotein RECK , suppression of tumorigenicity 15 , reversion-inducing-cysteine-rich protein with Kasal motifs

GENE ID SPECIES
8434 Homo sapiens
53614 Mus musculus
403477 Canis lupus familiaris
100519638 Sus scrofa
517232 Bos taurus
313488 Rattus norvegicus
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