RECK antibody (AA 23-212) (Biotin)

Catalog No. ABIN7167892

Product Details anti-RECK Antibody (Biotin)

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Binding Specificity: AA 23-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RECK antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Reversion-inducing cysteine-rich protein with Kazal motifs protein (23-212AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RECK

Target: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Alternative Name: RECK (RECK Products)

Synonyms: ST15 antibody, St15 antibody, mRECK antibody, reversion inducing cysteine rich protein with kazal motifs antibody, reversion-inducing-cysteine-rich protein with kazal motifs antibody, RECK antibody, Reck antibody

Background:

Background: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

Aliases: hRECK antibody, Membrane anchored glycoprotein (metastasis and invasion) antibody, RECK antibody, RECK protein antibody, RECK_HUMAN antibody, Reversion inducing cysteine rich protein with Kazal motifs antibody, Reversion-inducing cysteine-rich protein with Kazal motifs antibody, ST15 antibody, Suppression of tumorigenicity 15 (reversion inducing cysteine rich protein with kazal motifs) antibody, Suppressor of tumorigenicity 15 antibody, Suppressor of tumorigenicity 15 protein antibody

UniProt: O95980