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anti-Ring Finger Protein 139 (RNF139) Antibodies

The protein encoded by RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. Additionally we are shipping Ring Finger Protein 139 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF139 11236 Q8WU17
RNF139 75841 Q7TMV1
RNF139 315000  
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Top anti-Ring Finger Protein 139 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-RNF139 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB (1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Mouse Un-conjugated WB RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 on formalin-fixed paraffin-embedded human tonsil (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 7 to 9 Days
$484.00
Details
Bat Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to RNF139 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Dog Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$455.40
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA, WB Western Blot: RNF139 Antibody [NBP1-23027] - (1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details

RNF139 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Ring Finger Protein 139 Antibodies

  1. Human Polyclonal RNF139 Primary Antibody for ELISA, WB - ABIN564886 : Brauweiler, Lorick, Lee, Tsai, Chan, Weissman, Drabkin, Gemmill: RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene. in Oncogene 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal RNF139 Primary Antibody for IHC (p), ELISA - ABIN564887 : Adams, Simms, Abdelhamed, Dawe, Szymanska, Logan, Wheway, Pitt, Gull, Knowles, Blair, Cross, Sayer, Johnson: A meckelin-filamin A interaction mediates ciliogenesis. in Human molecular genetics 2012 (PubMed)

More Antibodies against Ring Finger Protein 139 Interaction Partners

Human Ring Finger Protein 139 (RNF139) interaction partners

  1. Low RNF139 expression is associated with progression of tongue cancer.

  2. interaction with Bag1 (show BAG1 Antibodies) then shifts hERG (show KCNH2 Antibodies) degradation to the membrane-anchored E3 ligase TRC8 and its E2-conjugating enzyme Ube2g2 (show UBE2G2 Antibodies), as determined by siRNA screening

  3. TRC8 and TMEM129 are endoplasmic reticulum-associated degradation ubiquitin E3 ligases for viral and cellular targeting of MHC class I. (Review)

  4. TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 (show HMOX1 Antibodies) for ubiquitination and degradation.

  5. TRC8 function may provide a regulatory link between the lipid and protein biosynthetic pathways.

  6. TRC8 modulation of sterol response element binding protein activity comprises a novel regulatory link between growth control and the cholesterol/lipid homeostasis pathway.

  7. The presence of diploid and tetraploid tumor cells with and without TRC8 deletions on the nontranslocated chromosome suggest that loss of the remaining normal allele of TRC8 may contribute to tumor development at later stages.

  8. TRC8 is a novel sterol-sensing endoplasmic reticulum membrane protein (show SLC39A6 Antibodies) that hinders SREBP-2 (show SREBF2 Antibodies) processing through interaction with SREBP-2 (show SREBF2 Antibodies) and SCAP (show SH2D2A Antibodies), regulating its own turnover rate by means of its E3 ubiquitin ligase (show MUL1 Antibodies) activity

  9. Data show that the TRC8 E3 ligase is required for MHC I dislocation from the ER and identify a new complex associated with mammalian ERAD.

Ring Finger Protein 139 (RNF139) Antigen Profile

Protein Summary

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Gene names and symbols associated with RNF139

  • ring finger protein 139 (RNF139) antibody
  • ring finger protein 139 (Rnf139) antibody
  • ring finger protein 139 (rnf139) antibody
  • ring finger protein 139 S homeolog (rnf139.S) antibody
  • 4930555P18Rik antibody
  • HRCA1 antibody
  • RCA1 antibody
  • rnf139 antibody
  • TRC8 antibody
  • zgc:175173 antibody

Protein level used designations for RNF139

E3 ubiquitin-protein ligase RNF139 , multiple membrane spanning receptor TRC8 , patched related protein translocated in renal cancer , translocation in renal carcinoma on chromosome 8 protein , RING finger protein 139 , ring finger protein 139 S homeolog

GENE ID SPECIES
11236 Homo sapiens
75841 Mus musculus
315000 Rattus norvegicus
420338 Gallus gallus
609422 Canis lupus familiaris
100067392 Equus caballus
100156613 Sus scrofa
788471 Bos taurus
100447707 Pongo abelii
100734055 Cavia porcellus
100357210 Oryctolagus cuniculus
100144552 Danio rerio
444792 Xenopus laevis
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