RUNX1T1 Proteins
RUNX1T1 encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression.
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Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-604) protein (His tag) Protein
Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-577) protein (His tag) Protein
Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-567) protein (GST tag) Protein
Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) protein (GST tag) Protein
Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein
Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag) Protein
RUNX1T1 Protein Profile
Protein Summary
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Gene names and symbols associated with RUNX1T1
- runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (runx1t1) antibody
- RUNX1 translocation partner 1 L homeolog (runx1t1.L) antibody
- RUNX1 translocation partner 1 (RUNX1T1) antibody
- runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (Runx1t1) antibody
- RUNX1 translocation partner 1 (Runx1t1) antibody
- AML1T1 antibody
- Cbfa2t1 antibody
- Cbfa2t1h antibody
- CDR antibody
- ETO antibody
- MTG8 antibody
- si:ch211-232j17.1 antibody
- wu:fi14b07 antibody
- zgc:154044 antibody
- ZMYND2 antibody
Protein level used designations for RUNX1T1
protein CBFA2T1 , MTG8 , MTG8/ETOb , expressed during postmitotic spinal neurons, most likely in motorneurons , acute myelogenous leukemia 1 translocation 1, cyclin-D related , core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related , eight twenty one protein , myeloid translocation gene on 8q22 , zinc finger MYND domain-containing protein 2 , CBFA2T1 identified gene homolog , acute myelogenous leukemia 1 translocation 1 protein , core-binding factor, runt domain, alpha subunit 2 , cyclin D-related , translocated to, 1
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