Runt-Related Transcription Factor 1 (RUNX1) ELISA Kits

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. Additionally we are shipping RUNX1 Antibodies (317) and RUNX1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RUNX1 12394 Q03347
RUNX1 861 Q01196
RUNX1 50662 Q63046
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Top RUNX1 ELISA Kits at antibodies-online.com

Showing 5 out of 11 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
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Human
  96 Tests Log in to see 2 to 3 Days
$480.00
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Human
  96 Tests Log in to see 1 to 2 Days
$898.33
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Human
  96 Tests Log in to see 2 to 3 Days
$525.00
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Human
  96 Tests Log in to see 2 to 3 Days
$525.00
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More ELISA Kits for RUNX1 Interaction Partners

Mouse (Murine) Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. RUNX1 promoted TGF-beta (show TGFB1 ELISA Kits)-induced partial EMT (show ITK ELISA Kits) by increasing transcription of the PI3K subunit p110delta, which mediated Akt (show AKT1 ELISA Kits) activation.

  2. The promoter regions of Runx1 is targets of STAT4 (show STAT4 ELISA Kits) and that STAT4 (show STAT4 ELISA Kits) binding during NK cell activation induces epigenetic modifications of Runx1 gene loci resulting in increased expression.

  3. Results suggest that AML1/ETO (show RUNX1T1 ELISA Kits) expression determines a more mobile and less adherent phenotype in preleukemic cells, therefore altering the interaction with the hematopoietic niche, potentially leading to the migration across the bone marrow barrier and to disease progression

  4. Gene expression profiling of HEPs revealed a RUNX1c-induced proinflammatory molecular signature, supporting previous studies demonstrating proinflammatory signaling as a regulator of HSC emergence.

  5. Histones showed limited activation in regions of single TF binding, while enhancers that bind NF-E2 and either RUNX1, FLI1 (show FLI1 ELISA Kits) or both TFs gave the highest signals for TF occupancy and H3K4me2; these enhancers associated best with genes activated late in MK maturation.

  6. the ability of Runx1 to induce endothelial-to-hematopoietic transition (EHT) in non-hemogenic endothelial cells depends on the anatomical location of the cell and the developmental age of the conceptus

  7. CDK6 (show CDK6 ELISA Kits) kinase activity negatively regulates the conversion of fat-storing cells into fat-burning cells by suppressing RUNX1, and may be a therapeutic target for the treatment of obesity and related metabolic diseases

  8. RUNX1 dosage plays a pivotal role in hemogenic endothelium maturation and the establishment of the hematopoietic system.

  9. These results suggest that RUNX1 may be an essential modulator in BMP9 (show GDF2 ELISA Kits)- induced osteogenic differentiation of mesenchymal stem cells.

  10. Loss of Runx1 and Runx2 (show RUNX2 ELISA Kits) inhibits prostate cell motility.

Human Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. The effect of FENDRR on cell proliferation, apoptosis and invasion and migration ability in protate cancer cells was suppressed by silence of RUNX1.

  2. KSRP (show KHSRP ELISA Kits), miR (show MLXIP ELISA Kits)-129, and RUNX1 participate in a regulatory axis to control the outcome of myeloid differentiation.

  3. PKM2 (show PKM ELISA Kits) as a novel target of RUNX1-ETO (show RUNX1T1 ELISA Kits) and is specifically downregulated in RUNX1-ETO (show RUNX1T1 ELISA Kits) positive AML patients, indicating that PKM2 (show PKM ELISA Kits) level might have a diagnostic potential in RUNX1-ETO (show RUNX1T1 ELISA Kits) associated AML.

  4. specific type of RUNX1 mutation did not affect its association pattern with trisomy 21

  5. High RUNX1 expression is associated with prostatic cancer.

  6. RUNX1 Mutation is associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  7. The specific association of ZBTB7A (show ZBTB7A ELISA Kits) mutations with t(8;21) rearranged acute myeloid leukaemia points towards leukemogenic cooperativity between mutant ZBTB7A (show ZBTB7A ELISA Kits) and the RUNX1/RUNX1T1 (show RUNX1T1 ELISA Kits) fusion protein has been reported.

  8. miR (show MLXIP ELISA Kits)-216a-3p can promote gastric cancer cell proliferation, migration, and invasion via targeting RUNX1 and activating the NF-kappaB (show NFKB1 ELISA Kits) signaling pathway

  9. the t(5;21)(p15 (show CDKN2B ELISA Kits);q22) translocation could be identified only when what had seemed like a del(21)(qq) in G-banded preparations was examined using FISH and RNA-sequencing directed at finding out what lay behind the 21q-.

  10. Our findings show the profound impact of RUNX1 allele dosage on gene expression profile and glucocorticoid sensitivity in AML, thereby opening opportunities for preclinical testing which may lead to drug repurposing and improved disease characterization.

Zebrafish Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Our data suggest that runx1 and cbfb are required at 2 different steps during early hematopoietic stem cell development

  2. We propose that cohesin and CTCF (show CTCF ELISA Kits) have distinct functions in the regulation of runx1 during zebrafish embryogenesis.

  3. Morpholino knockdown of Myef2 (show MYEF2 ELISA Kits) or Runx1 in zebrafish results in reduced numbers of hematopoietic stem cells, suggesting that these two factors also interact in vivo to regulate hematopoiesis.

  4. Runx1 is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  5. hematopoietic stem cell numbers depended on activity of the transcription factor Runx1, on blood flow, and on proper development of the dorsal aorta

  6. in zebrafish adult HSCs can be formed without an intact runx1.

  7. Zebrafish embryos lacking Rad21, or cohesin subunit Smc3, fail to express runx3 (show RUNX3 ELISA Kits) and lose hematopoietic runx1 expression in early embryonic development.

Xenopus laevis Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus.

  2. ETV6-RUNX1 (TEL-AML1) fusion and hyperdiploidy (>50 chromosomes) are favorable genetic features in childhood acute lymphoblastic leukemia (ALL).

  3. reveal a shift in Runx2 (show RUNX2 ELISA Kits) function protein during vertebrate evolution towards its exclusive roles in cartilage hypertrophy and bone differentiation within the amniote lineage

RUNX1 Antigen Profile

Antigen Summary

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX1

  • uncharacterized LOC473981 (LOC473981) antibody
  • runt-related transcription factor (runt) antibody
  • runt related transcription factor 1 (Runx1) antibody
  • runt related transcription factor 1 (RUNX1) antibody
  • runt-related transcription factor 1 (runx1) antibody
  • runt related transcription factor 1 L homeolog (runx1.L) antibody
  • runt-related transcription factor 1 (RUNX1) antibody
  • runt-related transcription factor 1 (Runx1) antibody
  • AI462102 antibody
  • aml antibody
  • aml-1 antibody
  • Aml1 antibody
  • aml1-evi-1 antibody
  • amlcr1 antibody
  • cbfa2 antibody
  • evi-1 antibody
  • Pebp2a2 antibody
  • pebp2ab antibody
  • Pebpa2b antibody
  • Runx-1 antibody
  • runx1 antibody
  • runxa antibody
  • XAML antibody
  • Xaml1 antibody

Protein level used designations for RUNX1

runt-related transcription factor 1 , runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) , runt-related transcription factor , runt protein , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core binding factor alpha 2 , core-binding factor subunit alpha-2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit , runt domain, alpha subunit 2 , AML1-EVI-1 fusion protein , core-binding factor, runt domain, alpha subunit 2 , aml1 , runt-related transcription factor a , runx1a , Acute myeloid leukemia 1 protein , Core-binding factor subunit alpha-2 , aml1 oncogene , ch-runtB2 , acute myeloid leukemia 1 , factor, runt domain, alpha subunit 2 , core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene) , runt related transcription factor 1

GENE ID SPECIES
473981 Pan troglodytes
100302713 Saccoglossus kowalevskii
12394 Mus musculus
861 Homo sapiens
58126 Danio rerio
379657 Xenopus laevis
396152 Gallus gallus
487746 Canis lupus familiaris
529631 Bos taurus
50662 Rattus norvegicus
100512633 Sus scrofa
100724149 Cavia porcellus
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