Runt-Related Transcription Factor 2 (RUNX2) ELISA Kits

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Additionally we are shipping RUNX2 Antibodies (253) and RUNX2 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RUNX2 860 Q13950
RUNX2 12393 Q08775
RUNX2 367218  
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Top RUNX2 ELISA Kits at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$700.00
Details
Mouse 0.116 ng/mL 0.31 ng/mL - 20 ng/mL Typical Standard Curve for Mouse RUNX2 ELISA. 96 Tests Log in to see 13 to 16 Days
$720.00
Details
Rat 0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rabbit 0.188 ng/mL 0.31 ng/mL - 20 ng/mL A typical standard curve 96 Tests Log in to see 13 to 16 Days
$576.62
Details
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Chicken 1.875 ng/mL 3.125-200 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced RUNX2 ELISA Kits

  1. Mouse (Murine) RUNX2 ELISA Kit for Sandwich ELISA - ABIN424555 : Yasukawa, Hayashi, Tanabe, Tsuda, Suzuki, Kawato, Suzuki, Maeno, Ogiso: Involvement of the calcium-sensing receptor in mineral trioxide aggregate-induced osteogenic gene expression in murine MC3T3-E1 cells. in Dental materials journal 2017 (PubMed)
    Show all 2 Pubmed References

  2. Human RUNX2 ELISA Kit for Sandwich ELISA - ABIN416824 : Nagy, Eriksson, Yousry, Caidahl, Ingelsson, Hansson, Franco-Cereceda, Bäck: Valvular osteoclasts in calcification and aortic valve stenosis severity. in International journal of cardiology 2013 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) RUNX2 ELISA Kit for Sandwich ELISA - ABIN822142 : Liu, Xiao, Shen, Chen, Xu, Zhao, Wu, Zhang, Zhong, Tang, Liu, Zhao, Zheng, Cao, Zu: MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification. in PLoS ONE 2017 (PubMed)

More ELISA Kits for RUNX2 Interaction Partners

Human Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Study identified RUNX2 to be targeted by miR (show MLXIP ELISA Kits)-217 which directly bound to RUNX2 mRNA and inhibited its expression in bladder cancer cells. Also, findings demonstrated that RUNX2 expression was upregulated by hsa_circ_0000144. Moreover, rescue assays demonstrated that RUNX2 was a downstream effector molecule of hsa_circ_0000144/miR (show MLXIP ELISA Kits)-217 network. These results revealed the oncogenic role of RUNX2 in bladder neoplasm.

  2. In summary, these results reveal that PTHLH expression is a poor prognosis marker in head and neck squamous cell carcinoma patients, and RUNX2-PTHLH axis contributes to head and neck squamous cell carcinoma tumor growth.

  3. Knockdown of RUNX2 significantly inhibited TE-1 and EC-109 cell viability, repressed TE-1 cell migration and invasion, and increased TE-1 cell apoptosis and were associated with the activation of the PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) and ERK (show EPHB2 ELISA Kits) pathways.

  4. Results show that RUNX2 gene silencing increased gemcitabine (GEM (show GEM ELISA Kits)) sensitivity of p53mutated pancreatic cancer (PaCa) MiaPaCa2 spheres suggesting that RUNX2 is involved in PaCa-GEM (show GEM ELISA Kits) resistance in presence of mutated p53 (show TP53 ELISA Kits).

  5. Runx2 overexpression effectively decreased TNF-alpha (show TNF ELISA Kits)-induced Bax (show BAX ELISA Kits) and cleaved caspase-3 (show CASP3 ELISA Kits) expression levels

  6. RUNX2 is one of the promising molecular targets for the treatment of the patients with pancreatic cancer regardless of their p53 (show TP53 ELISA Kits) status[review]

  7. we identified a novel missense mutation of RUNX2 in 2 patients by Whole exome sequencing and showed potential correlations between facial phenotypes and missense mutations in Runt (show RUNX1 ELISA Kits) domain through a mini-meta analysis.

  8. Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis.

  9. Results show that RUNX2 is highly expressed in bladder cancer tissues and are negatively correlated with miR (show MLXIP ELISA Kits)-154 levels. This is likely through miR (show MLXIP ELISA Kits)-154 binding the 3'-UTR (show UTS2R ELISA Kits) of RUNX2 mRNA, promoting its degradation.

  10. Results identified a novel mutation besides the previously known in one patient with cleidocranial dysplasia (CCD). G462X mutation in exon 8 is located in the C-terminus of proline/serine/threonine-rich (PST (show SULT1A1 ELISA Kits)) domain. It might reduce the Runx2 transacting activity, lower the protein stability, downgrade the expression of bone marker genes, and eventually diminish osteoblast differentiation in CCD patients.

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. This study reveals that RUNX2 is differentially expressed in ATII cells vs. fibroblasts in lung fibrosis, which contributes to profibrotic cell function. Cell-specific targeting of RUNX2 pathways may represent a therapeutic approach for IPF.

  2. we have identified novel interaction between p38 MAPK (show MAPK14 ELISA Kits) and Runx2 enhances Runx2 transactivity, thus promoting vascular smooth muscle cells calcification

  3. By using microRNA array, we identified a large number of microRNAs that showed different expression between wild-type Runx2 group and mutant groups. The aim of this study is to find out the effect of mmu-miR (show MLXIP ELISA Kits)-1963, which was downregulated in all mutant Runx2 groups, on the ameloblast differentiation of LS8 cells

  4. Results indicate that Dlx5 (show DLX5 ELISA Kits) and Runx2 are critical factors for the upregulated Osterix (show SP7 ELISA Kits) expression in shPP2A cells, which is considered to be important for the accelerated osteoblast differentiation in these cells.

  5. the expression of mouse Amtn gene in amelogenesis is mediated by Runx2/Cbfbeta complex. Runx2/Cbfbeta can bind to the two Runx2 binding motifs AACCACT (-1342/-1336) and AACCAAA (-98/-92) in the Amtn promoter and regulate Amtn gene expression.

  6. Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis.

  7. Puerarin may promote MC3T3E1 osteoblastlike cell viability and differentiation, which may be related to the downregulation of miR204 and the following activation of Runx2.

  8. mTOR (show FRAP1 ELISA Kits)/Raptor (show RPTOR ELISA Kits) signaling is essential for bone formation in vivo through the regulation of Runx2 expression.

  9. these findings provide evidence that Cx43 (show GJA1 ELISA Kits) and Runx2 functionally intersect in vivo to regulate cortical bone properties and affect osteoblast differentiation and proliferation

  10. miR (show MLXIP ELISA Kits)-133a-5p targets the 3' UTR (show UTS2R ELISA Kits) of RUNX2 mRNA to regulate the expression of RUNX2 negatively.

Rabbit Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. The results suggest that gene therapy using Runx2-modi fi ed dental pulp stem cells was more effective during bone deposition and new bone formation in tibia Distraction osteogenesis.

  2. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  3. The OPG (show TNFSF11 ELISA Kits) expression levels decreased while those of RANKL (show TNFSF11 ELISA Kits) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data also indicate that MGP (show MGP ELISA Kits) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

Pig (Porcine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Klotho (show KL ELISA Kits) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha-RUNX2 pathway.

RUNX2 Antigen Profile

Antigen Summary

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Gene names and symbols associated with RUNX2

  • runt related transcription factor 2 (RUNX2) antibody
  • runt-related transcription factor 2a (runx2a) antibody
  • runt related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (Runx2) antibody
  • runt related transcription factor 2 (runx2) antibody
  • runt-related transcription factor 2 (LOC703331) antibody
  • runt-related transcription factor 2 (LOC100549663) antibody
  • runt related transcription factor 2 L homeolog (runx2.L) antibody
  • runt-related transcription factor 2 (RUNX2) antibody
  • aml3 antibody
  • Cbf antibody
  • CBF-alpha-1 antibody
  • Cbfa-1 antibody
  • cbfa1 antibody
  • ccd antibody
  • ccd1 antibody
  • CLCD antibody
  • LS3 antibody
  • OSF-2 antibody
  • osf2 antibody
  • pea2aa antibody
  • pebp2a1 antibody
  • pebp2a2 antibody
  • pebp2aa antibody
  • pebp2aa1 antibody
  • Pebpa2a antibody
  • RUNX2 antibody

Protein level used designations for RUNX2

PEA2-alpha A , PEBP2-alpha A , SL3-3 enhancer factor 1 alpha A subunit , SL3/AKV core-binding factor alpha A subunit , acute myeloid leukemia 3 protein , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt-related transcription factor 2 , transcription factor Runx2a , AKV core binding factor , CBF-alpha-1 , PEBP2 alpha A , core binding factor alpha 1 , runt domain, alpha subunit 1 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , transcription factor Cbfa1 , runt-related factor 2 , core binding factor alpha 1 subunit , runt-related transcription factor 2-like , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II

GENE ID SPECIES
860 Homo sapiens
405784 Danio rerio
12393 Mus musculus
367218 Rattus norvegicus
373919 Gallus gallus
445986 Takifugu rubripes
472017 Pan troglodytes
703331 Macaca mulatta
100008943 Oryctolagus cuniculus
100033890 Equus caballus
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
100037059 Xenopus laevis
536911 Bos taurus
100737965 Sus scrofa
474923 Canis lupus familiaris
100734175 Cavia porcellus
100861217 Capra hircus
101115489 Ovis aries
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