Runt-Related Transcription Factor 3 (RUNX3) ELISA Kits

RUNX3 encodes a member of the runt domain-containing family of transcription factors. Additionally we are shipping RUNX3 Antibodies (231) and RUNX3 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RUNX3 12399  
RUNX3 864 Q13761
RUNX3 156726  
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Top RUNX3 ELISA Kits at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
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Human
  96 Tests Log in to see 2 to 3 Days
$495.00
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Human < 0.054 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
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More ELISA Kits for RUNX3 Interaction Partners

Zebrafish Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. In neuronal fate determination, Runx co-factor Cbfbeta is essential for its function, but the high level of Runx3 expression can overcome the loss of Cbfbeta, demonstrating that Cbfbeta in this context serves solely as a signal amplifier of Runx3 activity.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (show RUNX1 ELISA Kits)-expressing cells in the ventral wall of the dorsal aorta.

  4. Zebrafish embryos lacking Rad21, or cohesin subunit Smc3, fail to express runx3 and lose hematopoietic runx1 (show RUNX1 ELISA Kits) expression in early embryonic development.

Pig (Porcine) Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. These results demonstrate that the CRISPR/Cas9 system is effective in inducing mutations on a specific locus of genome and the RUNX3 knockout pigs can be useful resources for human cancer research and to develop novel cancer therapies.

Mouse (Murine) Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. The promoter regions of Runx3 is targets of STAT4 (show STAT4 ELISA Kits) and that STAT4 (show STAT4 ELISA Kits) binding during NK cell activation induces epigenetic modifications of Runx3 gene loci resulting in increased expression.

  2. Runx3 programs CD8 (show CD8A ELISA Kits)(+) T cell residency in non-lymphoid tissues and tumours; results provide insight into the signals that promote T cell residency in non-lymphoid sites, which could be used to enhance vaccine efficacy or adoptive cell therapy treatments that target cancer

  3. Findings suggest that Runx3 may regulate cell shape to inhibit melanoma cell migration partly through enhancing stress fiber formation and ECM (show MMRN1 ELISA Kits) protein production.

  4. The findings suggest that the absence of uPA (show PLAU ELISA Kits) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.

  5. Runx3-deficient CD8 (show CD8A ELISA Kits)(+) cytotoxic effector T cells aberrantly upregulated genes characteristic of follicular helper T (TFH) cell lineage, including Bcl6 (show BCL6 ELISA Kits), Tcf7 (show TCF7 ELISA Kits) and Cxcr5 (show CXCR5 ELISA Kits). Mechanistically, the Runx3-CBFbeta transcription factor complex deployed H3K27me3 to Bcl6 (show BCL6 ELISA Kits) and Tcf7 (show TCF7 ELISA Kits) genes to suppress the TFH program.

  6. Deletion of Runx3 in the peripheral nervous system or specifically in peripheral sensory neurons, or of enhancer elements driving Runx3 expression in proprioceptive neurons, induced prepubertal scoliosis.

  7. We found that Runx3 exerted a positive effect on early myeloid development

  8. Runx3 plays a crucial role in the hypothalamo-pituitary-gonadal axis

  9. intricate combinatorial interplay among the three regulatory elements governs Runx3 expression in distinct subtypes of TrkC (show NTRK3 ELISA Kits) neurons while concomitantly extinguishing its expression in non-TrkC (show NTRK3 ELISA Kits) neurons

  10. this study identifies a compensatory signaling mechanism that prevents lineage-fate errors by dynamically modulating Runx3d induction rates during MHC I positive selection

Human Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. MiR (show MLXIP ELISA Kits)-182/HOXA9 was involved in the process of RUNX3-mediated GC tumor growth.

  2. The BMP9 (show GDF2 ELISA Kits)-induced phosphorylation of Smad1 (show GARS ELISA Kits)/5/8 was increased with the overexpression of RUNX3, and yet was decreased with the knockdown of RUNX3. Collectively, our findings suggest that RUNX3 is an essential modulator of the BMP9 (show GDF2 ELISA Kits)-induced osteoblast lineage differentiation of mesenchymal stem cells (MSCs).

  3. results suggest that EZH2 (show EZH2 ELISA Kits) regulates cell proliferation potentially by targeting RUNX3 through the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway in laryngeal carcinoma.

  4. These findings suggested that RUNX3 played a tumor suppressor role in oral squamous cell carcinoma (OSCC) by inhibiting cell migration, invasion and angiogenesis, supporting that it could be a potential therapeutic target for OSCC

  5. Study showed that Runx3 was found a target of miR (show MLXIP ELISA Kits)-106b, and the inhibition of miR (show MLXIP ELISA Kits)-106b upregulated Runx3. These results provide evidence that Runx3 is a tumor-suppressor in retinoblastoma and is a target of miR (show MLXIP ELISA Kits)-106b.

  6. Our results support the ability of Runx3 to contribute to the dissemination of human PDAC thus confirming the observations from murine models.

  7. High expression of RUNX3 is correlated with gastric cancer.

  8. RUNX3 is a common downstream target of TGF-beta (show TGFB1 ELISA Kits) and Notch (show NOTCH1 ELISA Kits) signaling, and may be a novel therapeutic target for treating CVD mediated by EndMT.

  9. CNRIP1 (show Cnrip1 ELISA Kits) and RUNX3 as potential DNA methylation biomarkers for CRC (show CALR ELISA Kits) diagnosis and treatment

  10. RUNX3 expression in oral squamous carcinoma cells contributes to their bone invasion and the resulting osteolysis by inducing their malignant behaviors and production of osteolytic factors.

RUNX3 Antigen Profile

Antigen Summary

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX3

  • runt-related transcription factor 3 (runx3) antibody
  • runt-related transcription factor 3 (RUNX3) antibody
  • runt related transcription factor 3 (RUNX3) antibody
  • runt related transcription factor 3 (runx3) antibody
  • runt related transcription factor 3 L homeolog (runx3.L) antibody
  • runt related transcription factor 3 (Runx3) antibody
  • runt-related transcription factor 3 (Runx3) antibody
  • AML2 antibody
  • Cbfa3 antibody
  • frrunx3 antibody
  • Pebp2a3 antibody
  • PEBP2aC antibody
  • runx3 antibody
  • runxb antibody

Protein level used designations for RUNX3

runt-related transcription factor b , runt-related transcription factor 3 , core-binding factor 3 , frRunx3/p45 , CBF-alpha-3 , PEA2-alpha C , PEBP2-alpha C , SL3-3 enhancer factor 1 alpha C subunit , SL3/AKV core-binding factor alpha C subunit , acute myeloid leukemia 2 protein , core binding factor alpha 3 , core-binding factor subunit alpha-3 , oncogene AML-2 , polyomavirus enhancer-binding protein 2 alpha C subunit , runt domain, alpha subunit 3 , transcription factor AML2/CBFA3 , PEA2 alpha C , PEBP2 alpha C , acute myeloid leukemia gene 2 , core-binding factor, runt domain, alpha subunit 3 , transcription factor AML2 , Runt related transcription factor 3 , Runx3 MASN-variant

GENE ID SPECIES
58127 Danio rerio
403159 Sus scrofa
456633 Pan troglodytes
100049632 Takifugu rubripes
100474431 Ailuropoda melanoleuca
100500732 Xenopus laevis
12399 Mus musculus
864 Homo sapiens
617389 Bos taurus
156726 Rattus norvegicus
769687 Gallus gallus
487366 Canis lupus familiaris
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