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The protein encoded by S100A11 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Additionally we are shipping S100A11 Antibodies (142) and S100A11 Proteins (35) and many more products for this protein.
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Our present study indicated that S100A11 promotes EMT (show ITK ELISA Kits) through accumulation of TGF-beta1 (show TGFB1 ELISA Kits) expression, and TGF-beta1 (show TGFB1 ELISA Kits)-induced upregulation of p-SMAD2 (show SMAD2 ELISA Kits) and 3.
Results show that S100A11 expression is up-regulated by BC200 through stabilizing its mRNA and that S100A11 critically mediates the ability of BC200 RNA to induce cancer cell migration and invasion.
Furthermore, we identify flotillin-1 (FLOT1 (show FLOT1 ELISA Kits)) and histone H1 (show H1F0 ELISA Kits) as downstream factors for cytoplasmic and nuclear pathway of S100A11, which are required for LASP1 (show LASP1 ELISA Kits)-S100A11 axis-mediated epithelial-mesenchymal transition and colorectal cancer progression.
In patients with rheumatoid arthritis, S100A11 is up-regulated and is associated with inflammation and disease activity.
S100A11 overexpression correlates with an aggressive malignant phenotype and may constitute a novel prognostic factor for HGSC
S100A11 is involved in homologous recombination by regulating the appearance of RAD51 (show RAD51 ELISA Kits) in double strand break repair sites.
we studied S100A11 and noted knockdown of S100A11 using short hairpin RNA, which inhibited proliferation, invasion, and migration of renal carcinoma (show TSC2 ELISA Kits) cells as well as increased expression of E-cadherin (show CDH1 ELISA Kits) and decreased expression of epidermal growth factor receptor (show EGFR ELISA Kits)/Akt (show AKT1 ELISA Kits) in renal carcinoma (show TSC2 ELISA Kits) cells. Therefore, S100A11 may be a key molecular target for treating renal carcinoma (show TSC2 ELISA Kits).
higher S100A11 expression was associated with statistically significant decrease in disease-free survival in clear cell renal cell carcinoma (show MOK ELISA Kits)
the up-regulation of S100A11 plays a role in tumor progression, particularly in KRAS-mutated lung adenocarcinomas
metastatic cancer cells have elevated rate of cell injury and they rely on the S100A11-ANXA2 (show ANXA2 ELISA Kits) complex to enable cell membrane repair. S100A11 in a complex with Annexin A2 (show ANXA2 ELISA Kits) helps reseal the plasma membrane.
This work focused on S100A11, a dimeric EF-hand protein with two hydrophobic target binding sites. An annexin peptide (Ax) served as the target. Target binding is allosterically controlled by Ca(2 (show CA2 ELISA Kits)+) over a distance of approximately 26 A. Ca(2 (show CA2 ELISA Kits)+) promotes formation of a [Ca4 (show CA4 ELISA Kits) S100 Ax2] complex, where the Ax peptides are accommodated between helices III/IV and III'/IV'.
Studies show that monomeric S100B (show S100B ELISA Kits) and S100A11 proteins are alpha-helical and retain a significant amount of tertiary structure.
Endometrial S100A11 is a crucial intermediator in EGF (show EGF ELISA Kits)-stimulated embryo adhesion, endometrium receptivity, and immunotolerance via affecting Ca2 (show CA2 ELISA Kits)+ uptake and release from intracellular Ca2 (show CA2 ELISA Kits)+ stores.
S100A11 is the mouse counterpart of Xenopus dicalcin that suppresses the fertilization process through its action on cumulus cells, and thereby plays a key role in fertilization success in the mouse.
Following transformation by transglutaminase 2 (show TGM2 ELISA Kits), S100A11 acquires the capacity to signal through the p38 MAP kinase (show MAPK14 ELISA Kits) pathway, accelerate chondrocyte hypertrophy, and couple inflammation with chondrocyte activation to promote progression of osteoarthritis.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
, S100 calcium-binding protein A11 (calgizzarin)
, metastatic lymph node gene 70 protein
, protein S100-A11
, protein S100-C
, S100 calcium-binding protein A11
, S100 calcium binding protein A11 (calizzarin)
, S100C protein
, S100 calcium binding protein A11 (calgizzarin)
, S100 calcium binding protein A14
, endothelial monocyte activating polypeptide 1
, endothelial monocyte-activating polypeptide