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The protein encoded by S100A11 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Additionally we are shipping S100A11 Antibodies (120) and S100A11 Kits (66) and many more products for this protein.
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S100A11 overexpression correlates with an aggressive malignant phenotype and may constitute a novel prognostic factor for HGSC
S100A11 is involved in homologous recombination by regulating the appearance of RAD51 (show RAD51 Proteins) in double strand break repair sites.
we studied S100A11 and noted knockdown of S100A11 using short hairpin RNA, which inhibited proliferation, invasion, and migration of renal carcinoma cells as well as increased expression of E-cadherin and decreased expression of epidermal growth factor receptor/Akt in renal carcinoma cells. Therefore, S100A11 may be a key molecular target for treating renal carcinoma.
higher S100A11 expression was associated with statistically significant decrease in disease-free survival in clear cell renal cell carcinoma (show MOK Proteins)
the up-regulation of S100A11 plays a role in tumor progression, particularly in KRAS-mutated lung adenocarcinomas
metastatic cancer cells have elevated rate of cell injury and they rely on the S100A11-ANXA2 (show ANXA2 Proteins) complex to enable cell membrane repair. S100A11 in a complex with Annexin A2 (show ANXA2 Proteins) helps reseal the plasma membrane.
All three markers correlated significantly with regional lymph node metastasis: FXYD3 (show FXYD3 Proteins) (p = 0.0110), S100A11 (p = 0.0071), and GSTM3 (show glutathione S-transferase mu 3 (brain) Proteins) (p = 0.0173) in colon cancer lymphatic metastasis.
The EGFRvIII-STAT3 (show STAT3 Proteins) pathway promotes cell migration and invasion by upregulating S100A11 in hepatocellular carcinoma.
Proteomic data suggest a limited protein set is involved in SET- (template activating factor-I-) mediated cytotoxicity of TCE (trichloroethylene) in hepatocytes; this set includes CFL1 (cofilin 1 (show CFL1 Proteins)), PRDX2 (peroxiredoxin 2 (show PRDX2 Proteins)), and S100-A11 (calgizzarin).
Our data indicate that S100A11 overexpression exerts a protumoral functional role in papillary thyroid carcinoma pathogenesis.
Studies show that monomeric S100B (show S100B Proteins) and S100A11 proteins are alpha-helical and retain a significant amount of tertiary structure.
Endometrial S100A11 is a crucial intermediator in EGF (show EGF Proteins)-stimulated embryo adhesion, endometrium receptivity, and immunotolerance via affecting Ca2 (show CA2 Proteins)+ uptake and release from intracellular Ca2 (show CA2 Proteins)+ stores.
S100A11 is the mouse counterpart of Xenopus dicalcin that suppresses the fertilization process through its action on cumulus cells, and thereby plays a key role in fertilization success in the mouse.
Following transformation by transglutaminase 2 (show TGM2 Proteins), S100A11 acquires the capacity to signal through the p38 MAP kinase (show MAPK14 Proteins) pathway, accelerate chondrocyte hypertrophy, and couple inflammation with chondrocyte activation to promote progression of osteoarthritis.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
, S100 calcium-binding protein A11 (calgizzarin)
, metastatic lymph node gene 70 protein
, protein S100-A11
, protein S100-C
, S100 calcium-binding protein A11
, S100 calcium binding protein A11 (calizzarin)
, S100C protein
, S100 calcium binding protein A11 (calgizzarin)
, S100 calcium binding protein A14
, endothelial monocyte activating polypeptide 1
, endothelial monocyte-activating polypeptide