S100A11 Protein (His tag)
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- Target See all S100A11 Proteins
- S100A11 (S100 Calcium Binding Protein A11 (S100A11))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This S100A11 protein is labelled with His tag.
- Purpose
- Recombinant Mouse S100A11 Protein (His Tag)(Active)
- Sequence
- Met1-Ile98
- Characteristics
- Recombinant Mouse S100-A11 is produced by our E.coli expression system and the target gene encoding Met1-Ile98 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human ANXA2(Cat: PKSH032074) at 10μg/ml(100 μl/well) can bind Mouse S100A11-His. The ED50 of Mouse S100A11-His is 0.8μg/mL.
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S100 Calcium Binding Protein A11 (S100A11) (AA 1-105) protein (His-IF2DI Tag)
S100A11 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
S100 Calcium Binding Protein A11 (S100A11) (AA 1-105) protein (GST tag)S100A11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
S100 Calcium Binding Protein A11 (S100A11) (AA 10-87) protein (GST tag)S100A11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
S100 Calcium Binding Protein A11 (S100A11) (AA 1-98) protein (Strep Tag)Crystallography grade S100A11 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
S100 Calcium Binding Protein A11 (S100A11) (AA 2-105) protein (His tag)Crystallography grade S100A11 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- S100A11 (S100 Calcium Binding Protein A11 (S100A11))
- Alternative Name
- S100A11 (S100A11 Products)
- Synonyms
- MLN70 Protein, S100C Protein, PCALG Protein, EMAPI Protein, Emap1 Protein, S100a14 Protein, S100c Protein, cal Protein, S100 calcium binding protein A11 Protein, S100A11 Protein, S100a11 Protein
- Background
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Background: Protein S100-A11(S100A11) is a member of the S-100 family. S100A11 is widely expressed in multi pletissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth mediator, S100A11 acts as either a tumor suppressor or promoter in many different types of tumors and would play respective roles in influencing the proliferatin of the cancer cells. In the nucleus, S100A11 suppresses the growth of keratinocytes through p21 (CIP1/WAF1) activation and induces cell differentiation. S100A11 is also a novel diagnostic marker in breast carcinoma.
Synonym: Protein S100-A11, Calgizzarin, Endothelial monocyte-activating polypeptide, EMAP, Protein S100-C, S100 calcium-binding protein A11, S100a11, S100c,cal,Emap1,EMAPI,S100A11,S100a14,S100c
- Molecular Weight
- 12.6 kDa
- UniProt
- P50543
- Pathways
- S100 Proteins
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