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S100A11 Protein (His tag)

S100A11 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE
Catalog No. ABIN7320359
  • Target See all S100A11 Proteins
    S100A11 (S100 Calcium Binding Protein A11 (S100A11))
    Protein Type
    Recombinant
    Origin
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    Mouse
    Source
    • 16
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This S100A11 protein is labelled with His tag.
    Purpose
    Recombinant Mouse S100A11 Protein (His Tag)
    Sequence
    Met1-Ile98
    Characteristics
    A DNA sequence encoding the mouse S100A11 (NP_058020.1) (Met1-Ile98) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    > 90 % as determined by SDS-PAGE
    Top Product
    Discover our top product S100A11 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, 10 % glycerol, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    S100A11 (S100 Calcium Binding Protein A11 (S100A11))
    Alternative Name
    S100A11 (S100A11 Products)
    Synonyms
    MLN70 Protein, S100C Protein, PCALG Protein, EMAPI Protein, Emap1 Protein, S100a14 Protein, S100c Protein, cal Protein, S100 calcium binding protein A11 Protein, S100A11 Protein, S100a11 Protein
    Background

    Background: Protein S100-A11, also known as S100 calcium-binding protein A11, S100A11 and MLN70, is a member of the S-100 family. S100A11 is widely expressed in multiple tissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth mediator, S100A11 acts as either a tumor suppressor or promoter in many different types of tumors and would play respective roles in influencing the proliferation of the cancer cells. In the nucleus, S100A11 suppresses the growth of keratinocytes through p21 (CIP1/WAF1) activation and induces cell differentiation. S100A11 is also a novel diagnostic marker in breast carcinoma.

    Synonym: Protein S100-A11; Calgizzarin; Endothelial monocyte-activating polypeptide; EMAP; Protein S100-C; S100 calcium-binding protein A11; S100a11; S100c;cal;Emap1;EMAPI;S100A11;S100a14;S100c

    Molecular Weight
    13.2 kDa
    NCBI Accession
    NP_058020
    Pathways
    S100 Proteins
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