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The protein encoded by SEC13 belongs to the SEC13 family of WD-repeat proteins. Additionally we are shipping SEC13 Antibodies (75) and and many more products for this protein.
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the knockdown of nucleoporins NPP-10, NPP-13 and NPP-20 in Caenorhabditiselegans affects early steps in centromere formation and sister centromere resolution, and results in severe chromosomal defects in the early embryo.
TRAPPC12, but not TRAPPC8, bound to Sec13/Sec31A tetramer but each Sec protein alone could not interact with TRAPPC12.
we demonstrated Sec13 as a novel component that was involved in VISA-mediated antiviral signaling pathway.
GNL2 and SEC13 are required for nonsense-mediated mRNA decay pathway in human cells.
When embedded in a three-dimensional matrix, Sec13-depleted Caco-2 cells form cysts but, unlike controls, are defective in lumen expansion.
three-dimensional reconstruction of Sec13/31 cages at 30 A resolution using cryo-electron microscopy and single particle analysis
Determine crystal structure of Sec13-Nup145C dimer.
Data show that coupling of the Sec23/24 and Sec13/31 layers of the COPII coat is required to drive export of collagen from the endoplasmic reticulum, and that efficient COPII assembly is essential for normal craniofacial development during embryogenesis.
The identified Sec13 interaction to PS1 is a new candidate interaction for linking PS1 to secretory and protein degrading vesicular circuits.
Sec13 regulates specific expression of immune factors with key functions in inflammation.
The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.
SEC13-like 1 isoform
, SEC13-like protein 1
, SEC13-related protein
, protein SEC13 homolog
, SEC13 related
, SEC13-like 1