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SETD8 Proteins

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins.

10 results:

SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-393) protein (His tag) Protein

SETD8 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3093468
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-349) protein (His tag) Protein

SETD8 Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3134954
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (His tag) Protein

SETD8 Origin: Human Source: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2731881
$302.50
Plus shipping costs $45.00 and $24.00 dry ice
50 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) Protein Protein

SETD8 Origin: Human Source: Escherichia coli (E. coli) Recombinant > 98 % as determined by SDS-PAGE SDS
Catalog No. ABIN2004726
$506.74
Plus shipping costs $45.00
100 μg (More quantities available)
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Delivery in 11 to 13 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (GST tag) Protein

SETD8 Origin: Human Source: Baculovirus infected Insect Cells, Insect cells (Sf9) WB
Catalog No. ABIN6700509
$289.00
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Delivery in 1 to 2 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) protein (His tag) Protein

SETD8 Origin: Human Source: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN5855179
$553.85
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 13 to 16 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) protein (GST tag) Protein

SETD8 Origin: Human Source: Baculovirus infected Insect Cells, Insect cells (Sf9) WB
Catalog No. ABIN6700508
$562.00
Plus shipping costs $45.00 and $24.00 dry ice
50 μg
local_shipping Shipping to: United States
Delivery in 1 to 2 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-336) protein (His tag) Protein

SETD8 Origin: Xenopus tropicalis Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1618348
$2,907.67
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-352) protein (His tag) Protein

SETD8 Origin: Cow Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1623210
$2,959.00
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days
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SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 1-429) protein (His tag) Protein

SETD8 Origin: Schizosaccharomyces pombe Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1591430
$3,197.33
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days
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  • Type Protein
    • Protein
  • Target SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
    • SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 2 (IL2)
    • Interleukin 1, beta (IL1B)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
    • Ferrochelatase, HEMH (HEMH)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Crystallization (Crys)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reactivity
    • Human
    • Cow
    • Mouse
    • Schizosaccharomyces pombe
    • Xenopus tropicalis
  • Images available
  • Host
    • Baculovirus infected Insect Cells
    • Yeast
    • Escherichia coli (E. coli)
    • Insect Cells
    • Insect cells (Sf9)
  • Binding Specificity
    • AA 195-352
    • AA 1-336
    • AA 1-349
    • AA 1-352
    • AA 1-393
    • AA 1-429
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

SETD8 Protein Profile

Protein Summary

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).

Gene names and symbols associated with SETD8

  • lysine methyltransferase 5A (KMT5A) antibody
  • lysine methyltransferase 5A (Kmt5a) antibody
  • lysine methyltransferase 5Ab (kmt5ab) antibody
  • lysine methyltransferase 5A S homeolog (kmt5a.S) antibody
  • 2410195B05Rik antibody
  • AA617402 antibody
  • AW536475 antibody
  • kmt5a antibody
  • kmt5a-a antibody
  • Pr-set7 antibody
  • RGD1305893 antibody
  • SET07 antibody
  • SET8 antibody
  • setd8 antibody
  • setd8-a antibody
  • setd8b antibody
  • wu:fc23f12 antibody
  • zgc:171649 antibody

Protein level used designations for SETD8

H4-K20-HMTase SETD8 , H4-K20-specific histone methyltransferase , H4K20-specific histone methyltransferase splice variant Set8b , N-lysine methyltransferase SETD8 , PR/SET domain containing protein 8 , PR/SET domain-containing protein 07 , PR/SET07 , SET domain-containing protein 8 , histone-lysine N-methyltransferase SETD8 , lysine N-methyltransferase 5A , PR-Set7 , SET domain-containing 8 , SET domain containing (lysine methyltransferase) 8b , SET domain containing 8b , N-lysine methyltransferase KMT5A , SET domain containing (lysine methyltransferase) 8 , histone methyltransferase Pr-set7/Set8 , lysine (K)-specific methyltransferase 5A , Histone-lysine N-methyltransferase KMT5A-A , Lysine-specific methylase 5A-A , N-lysine methyltransferase KMT5A-A , N-lysine methyltransferase SETD8-A , SET domain-containing protein 8-A , histone-lysine N-methyltransferase KMT5A-A , histone-lysine N-methyltransferase SETD8-A , lysine (K)-specific methyltransferase 5A S homeolog , lysine-specific methylase 5A-A

GENE ID SPECIES
387893 Homo sapiens
67956 Mus musculus
532622 Bos taurus
100004770 Danio rerio
689820 Rattus norvegicus
100158384 Xenopus laevis

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