SETD8 Proteins

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins.

Data Quality
  • 3
Type
  • 10
    Protein
Antigen
  • 10
Reactivity
  • 6
  • 1
  • 1
  • 1
  • 1
Application
  • 5
  • 4
  • 4
  • 2
  • 1
Host
  • 3
  • 3
  • 2
  • 2
  • 2
Binding Specificity
  • 2
  • 1
  • 1
  • 1
  • 1
Conjugate
  • 1
  • 7
  • 2
Protein Type
  • 8
Format
  • 5
  • 4
10 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3093468
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3134954
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2731881
$302.50
50 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Baculovirus infected Insect Cells, Insect cells (Sf9) (Source)
ReactivityHuman
Application WB
Order details Cat. No. ABIN6700509
$289.00
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 1 to 2 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 98 % as determined by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2004726
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Recombinant Protein, Baculovirus infected Insect Cells (Source), Purity > 85 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5855179
$553.85
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Baculovirus infected Insect Cells, Insect cells (Sf9) (Source)
ReactivityHuman
Application WB
Order details Cat. No. ABIN6700508
$562.00
50 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 1 to 2 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityXenopus tropicalis
Application ELISA
Order details Cat. No. ABIN1618348
$2,907.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1623210
$2,959.00
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivitySchizosaccharomyces pombe
Application ELISA
Order details Cat. No. ABIN1591430
$3,197.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
  • <
  • 1
  • >

SETD8 Protein Profile

Protein Summary

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).

Gene names and symbols associated with SETD8

  • lysine methyltransferase 5A (KMT5A) antibody
  • lysine methyltransferase 5A (Kmt5a) antibody
  • lysine methyltransferase 5Ab (kmt5ab) antibody
  • lysine methyltransferase 5A S homeolog (kmt5a.S) antibody
  • 2410195B05Rik antibody
  • AA617402 antibody
  • AW536475 antibody
  • kmt5a antibody
  • kmt5a-a antibody
  • Pr-set7 antibody
  • RGD1305893 antibody
  • SET07 antibody
  • SET8 antibody
  • setd8 antibody
  • setd8-a antibody
  • setd8b antibody
  • wu:fc23f12 antibody
  • zgc:171649 antibody

Protein level used designations for SETD8

H4-K20-HMTase SETD8 , H4-K20-specific histone methyltransferase , H4K20-specific histone methyltransferase splice variant Set8b , N-lysine methyltransferase SETD8 , PR/SET domain containing protein 8 , PR/SET domain-containing protein 07 , PR/SET07 , SET domain-containing protein 8 , histone-lysine N-methyltransferase SETD8 , lysine N-methyltransferase 5A , PR-Set7 , SET domain-containing 8 , SET domain containing (lysine methyltransferase) 8b , SET domain containing 8b , N-lysine methyltransferase KMT5A , SET domain containing (lysine methyltransferase) 8 , histone methyltransferase Pr-set7/Set8 , lysine (K)-specific methyltransferase 5A , Histone-lysine N-methyltransferase KMT5A-A , Lysine-specific methylase 5A-A , N-lysine methyltransferase KMT5A-A , N-lysine methyltransferase SETD8-A , SET domain-containing protein 8-A , histone-lysine N-methyltransferase KMT5A-A , histone-lysine N-methyltransferase SETD8-A , lysine (K)-specific methyltransferase 5A S homeolog , lysine-specific methylase 5A-A

GENE ID SPECIES
387893 Homo sapiens
67956 Mus musculus
532622 Bos taurus
100004770 Danio rerio
689820 Rattus norvegicus
100158384 Xenopus laevis
Did you look for something else?