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SLAMF8 encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. Additionally we are shipping SLAMF8 Antibodies (94) and SLAMF8 Kits (3) and many more products for this protein.
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Thus, SLAMF8 is involved in oncogenic KIT-mediated RAS-RAF- ERK signalling and the subsequent growth of human neoplastic mast cells mediated by SHP-2.
Slamf1 and Slamf8 govern ROS-dependent innate immune responses of myeloid cells.
Slamf8 was found to be a negative regulator of Nox2 activity in bacterial phagosomes.
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
SLAM family member 8
, B lymphocyte activator macrophage expressed
, B-lymphocyte activator macrophage expressed
, BCM-like membrane protein