Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. Additionally we are shipping SHPRH Antibodies (86) and and many more products for this protein.
Showing 2 out of 4 products:
This study suggests that SHPRH could be a link between mTOR (show FRAP1 ELISA Kits)-mediated epigenetic regulations and rRNA transcription, while concomitantly affecting genomic integrity.
evidence that SHPRH functions in rRNA transcription through its interaction with histone H3 (show HIST3H3 ELISA Kits) in a mammalian target of rapamycin (mTOR (show FRAP1 ELISA Kits))-dependent manner
HLTF (show HLTF ELISA Kits) and SHPRH suppress mutagenesis in a damage-specific manner, preventing mutations induced by UV rays and methyl methanesulfonate.
SHPRH maps to 6q24 and is a possible candidate for the tumor suppressor gene reported from that region.
SHPRH function is an important deterrent to mutagenesis and carcinogenesis in humans
We report that a putative tumor suppressor gene, SHPRH, is a human orthologue of yeast RAD5.The yRad5/SHPRH-dependent pathway is a conserved and fundamental DNA repair mechanism that protects the genome from genotoxic stress.
HLTF (show HLTF ELISA Kits) and SHPRH are functional homologues of yeast Rad5 that cooperatively mediate PCNA (show PCNA ELISA Kits) polyubiquitination and maintain genomic stability.
SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006
, E3 ubiquitin-protein ligase SHPRH
, SNF2, histone-linker, PHD and RING finger domain-containing helicase
, SNF2 histone linker PHD RING helicase