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SHPRH Products

(SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH))

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SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008].

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Featured SHPRH Categories

SHPRH Antibodies

High quality antibodies with extensive validation data.

SHPRH ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended SHPRH Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7151213
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7244009
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN566993
Quantity 50 μL
Datasheet Datasheet

Recommended SHPRH ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1131316
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1131317
Quantity 96 tests
Datasheet Datasheet

Recommended SHPRH Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319965
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SHPRH products

Lee, An, Park, Liaw, Woodgate, Park, Myung: "SHPRH regulates rRNA transcription by recognizing the histone code in an mTOR-dependent manner." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 17, pp. E3424-E3433, (2018) (PubMed).

Zhang, Fox, Park, Elliott, Rai, Cai, Sakamuru, Huang, Xia, Lee, Jeon, Mathew, Park, Edelmann, Park, Hong, Maloney, Myung: "A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies." in: Cancer research, Vol. 76, Issue 14, pp. 4183-91, (2016) (PubMed).

Zeman, Lin, Freire, Cimprich: "DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis." in: The Journal of cell biology, Vol. 206, Issue 2, pp. 183-97, (2014) (PubMed).

Motegi, Liaw, Lee, Roest, Maas, Wu, Moinova, Markowitz, Ding, Hoeijmakers, Myung: "Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 34, pp. 12411-6, (2008) (PubMed).

Motegi, Sood, Moinova, Markowitz, Liu, Myung: "Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination." in: The Journal of cell biology, Vol. 175, Issue 5, pp. 703-8, (2006) (PubMed).

Sood, Makalowska, Galdzicki, Hu, Eddings, Robbins, Moses, Namkoong, Chen, Trent: "Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region." in: Genomics, Vol. 82, Issue 2, pp. 153-61, (2003) (PubMed).

Synonyms and alternative names related to SHPRH

SNF2 histone linker PHD RING helicase (SHPRH), SNF2 histone linker PHD RING helicase (Shprh), 2610103K11Rik, AA450458, AU024614, bA545I5.2, BC006883, D230017O13Rik, E130018M05

Protein level used designations for SHPRH

  • 2610103K11Rik
  • E3 ubiquitin-protein ligase SHPRH
  • SNF2, histone-linker, PHD and RING finger domain-containing helicase
  • SNF2 histone linker PHD RING helicase
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