SRY (Sex Determining Region Y)-Box 3 (SOX3) ELISA Kits

SOX3 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX3 Antibodies (73) and SOX3 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SOX3 6658 P41225
SOX3 20675  
SOX3 679158  
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Top SOX3 ELISA Kits at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 46.875 pg/mL 78.125-5000 pg/mL Typical standard curve 96 Tests Log in to see 12 to 14 Days
$630.00
Details
Mouse 0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 12 to 14 Days
$630.00
Details
Rat 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 46.875 pg/mL 78.125-5000 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 2.344 pg/mL 3.906-250 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for SOX3 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. Pathogenic missense mutation in SOX3 gene is associated with intellectual disability, microphthalmia, coloboma, hypopituitarism, facial dysmorphology and dental anomalies, including microcephaly, retrognathia and a solitary median maxillary central incisor amongst other features.

  2. our data indicate that SOX3 may serve as an oncogene (show RAB1A ELISA Kits) in osteosarcoma

  3. deletion of the SOX3 gene may have a role in intellectual disability with hemophilia B

  4. Results show that SOX3 is upregulated in human osteosarcoma (OS) tissues and provide evidence that SOX3 promotes migration, invasiveness, and EMT (show ITK ELISA Kits) in OS cells via transcriptional activation of Snail1 (show SNAI1 ELISA Kits) expression.

  5. we provide a first map of the epigenetic landscape of SOX3 in pluripotent cells and during the early phases of neural differentiation. We found SOX3 gene to be non methylated from undifferentiated NT2/D1 to cells committed towards neural lineage.

  6. These findings demonstrate the novel mechanism by which Sox3 contributes to endometrial cancer stem cell invasion and suggest that repression of Sox3 by microRNA-194 may have therapeutic potential to suppress endometrial carcinoma metastasis. The cancer stem cell marker, CD133, might be the surface marker of endometrial cancer stem cell.

  7. Data indicate that SRY-box 3 transcription factor SOX-3 targets Src kinase (show CSK ELISA Kits) in epithelial ovarian cancer (EOC) cells.

  8. SOX3 overdosage permits normal sex development in 46,XX individuals with random X inactivation.

  9. Translocations interrupting this region may also affect the gonadal development, possibly depending on the chromatin context of the recipient chromosome. SOX3 duplications may substitute SRY (show SRY ELISA Kits) in some XX subjects

  10. Screening for SOX3 should be advised not only for hypopituitary patients with an ectopic posterior pituitary, but also for those with a structurally normal pituitary

Mouse (Murine) SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. CRISPR/Cas9-assisted gene swap provides strong evidence that SOX2 (show SOX2 ELISA Kits) and SOX3 proteins are functionally equivalent in developing brain and testes.

  2. Sox3 null mice exhibit a ventral extension of the anterior pituitary that penetrates, and generates a mass beneath, the sphenoid bone

  3. These data define Dbx1 as a direct SOX3 target gene.

  4. Sox2 (show SOX2 ELISA Kits) and Sox3 play a role in central nervous system glia and provide mechanistic insights into their function during differentiation processes.

  5. findings show SOX3 expression is maintained throughout telencephalic neurogenesis and is restricted to progenitor cells with neuroepithelial and radial glial morphologies; it is expressed within adult neurogenic regions; expression within the developing hypothalamus is upregulated in developing neurons and is maintained in a subset of differentiated hypoththalamic cells

  6. Subcommissural organ function is essential for the prevention of hydrocephalus and overexpression of Sox3 in the dorsal midline alters progenitor cell differentiation in a dose-dependent manner.

  7. It was shown that Sox2 (show SOX2 ELISA Kits) and Sox3 are dose-dependent regulators of sonic hedgehog (show SHH ELISA Kits) transcription that directly bind and activate a long-range Shh (show SHH ELISA Kits) forebrain enhancer.

  8. In neural precursor cells , Sox3 binds genes that are later bound and activated by Sox11 in differentiating neurons (Sox2 (show SOX2 ELISA Kits))

  9. The results indicate that Sox3 functions in an intrinsic manner to promote differentiation of spermatogonia in prepubertal mice but it is not required for ongoing spermatogenesis in adults.

  10. in a transgenic line, Sox3 was ectopically expressed in the bipotential gonad and this led to frequent complete XX male sex reversal

Zebrafish SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. these findings show that sox2 (show SOX2 ELISA Kits) and sox3 are together required for proper otic induction, but the level of expression must be tightly regulated to avoid suppression of differentiation and maintenance of pluripotency.

  2. these data show that sox2 (show SOX2 ELISA Kits) and sox3 exhibit intrinsic differences in promoting sensory vs. neural competence, but at high levels these factors can mimic each other to enhance both states. Regional cofactors like pax2a and fgf8 (show FGF8 ELISA Kits) also modify sox2 (show SOX2 ELISA Kits)/3 functions.

  3. significant decreases in sox3 (up to 3-fold) expression following chilling. Significant increases in expression of sox3 (up to 33-fold) during warming of chilled zebrafish embyos.

  4. Knockdown of fgf24 or sox3 causes severe epibranchial deficiencies but has little effect on otic development

  5. Knockdown of the four B1 sox (show PIPOX ELISA Kits) genes sox2 (show SOX2 ELISA Kits)/3/19a/19b resulted in severe developmental abnormalities.

  6. The pro-neural effects of Sox3 can compensate for inhibition of fibroblast growth factor (Fgf) signalling in inducing neural tissue but it is not sufficient to maintain neural fate, suggesting the presence of Sox3-independent roles of Fgf at later stages.

Xenopus laevis SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. Sox2 (show SOX2 ELISA Kits) is necessary for spinal cord regeneration and suggest a model whereby spinal cord injury activates proliferation of Sox2 (show SOX2 ELISA Kits)/3 expressing cells and their differentiation into neurons, a mechanism that is lost in non-regenerative froglets.

  2. XSeb4R (show RBM38 ELISA Kits) protein bound specifically to the 3'UTR (show UTS2R ELISA Kits) of Sox3 mRNA. XSeb4R (show RBM38 ELISA Kits) gain-of-function in ectodermal explants revealed increased stability of the maternal Sox3 transcripts, associated with a robust Sox3 protein production.

  3. knockdown of Oct91 inhibits neural induction driven by either Sox2 (show SOX2 ELISA Kits) or Sox3.

  4. Animal pole localized Sox3 acts to inhibit Nodal (Xnr5 and Xnr6) expression, and induces the expression of genes (Ectodermin, Xema, and Coco (show DAND5 ELISA Kits)) whose products repress Nodal signaling.

  5. Results demonstrate that both sox3 and sox2 are induced in response to BMP antagonism, but by distinct mechanisms and that the activation of both genes is independent of FGF signaling; however, both require FGF for the maintenance of their expression.

  6. Eya1 and Six1 are required for both the regulation of placodal neuronal progenitor proliferation, through their effects on SoxB1 expression, and subsequent neuronal differentiation.

SOX3 Antigen Profile

Antigen Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.

Gene names and symbols associated with SOX3

  • SRY-box 3 (SOX3) antibody
  • transcription factor SOX-3 (Tsp_06143) antibody
  • SRY-box 3 (sox3) antibody
  • SRY (sex determining region Y)-box 3 (Sox3) antibody
  • SRY (sex determining region Y)-box 3 (sox3) antibody
  • SRY-box 3 S homeolog (sox3.S) antibody
  • SRY-box 3 (Sox3) antibody
  • CH3 antibody
  • fc93f07 antibody
  • GHDX antibody
  • id:ibd2036 antibody
  • mrgh antibody
  • PHP antibody
  • PHPX antibody
  • sb:cb493 antibody
  • Sox-3 antibody
  • sox3-a antibody
  • soxb antibody
  • Sry antibody
  • wu:fc93f07 antibody
  • wu:fd02a08 antibody
  • Xlsox3 antibody
  • xSox-B1 antibody
  • xSox3 antibody
  • Xtsox3 antibody
  • zgc:110279 antibody

Protein level used designations for SOX3

transcription factor SOX-3 , SRY-related protein CH3 , cSox3 , transcription factor SOX3 , transcription factor Sox-3 , SRY (sex determining region Y)-box 3 , 2036 , transcription factor Sox-3-A , xSox3 , LOW QUALITY PROTEIN: transcription factor SOX-3 , SRY-box containing gene 3

GENE ID SPECIES
6658 Homo sapiens
374019 Gallus gallus
10911545 Trichinella spiralis
493228 Xenopus (Silurana) tropicalis
100349101 Oryctolagus cuniculus
20675 Mus musculus
30529 Danio rerio
399335 Xenopus laevis
492178 Canis lupus familiaris
781679 Bos taurus
100623770 Sus scrofa
679158 Rattus norvegicus
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