SENP6 Proteins
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin.
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SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1-1112) protein (His tag) Protein
SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1-1132) protein (His tag) Protein
SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1-110) protein (GST tag) Protein
SENP6 Protein Profile
Protein Summary
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA\; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000
Gene names and symbols associated with SENP6
- SUMO1/sentrin specific peptidase 6 (SENP6) antibody
- SUMO/sentrin specific peptidase 6 (Senp6) antibody
- SUMO1/sentrin specific peptidase 6 (Senp6) antibody
- SUMO1/sentrin specific peptidase 6a (senp6a) antibody
- 2810017C20Rik antibody
- E130319N12Rik antibody
- fc83h02 antibody
- im:7148342 antibody
- mKIAA0797 antibody
- SSP1 antibody
- Susp1 antibody
- wu:fc83h02 antibody
- zgc:171230 antibody
Protein level used designations for SENP6
2810017C20Rik , SUMO-1-specific protease 1 , SUMO1/sentrin specific protease 6 , sentrin-specific protease 6 , sentrin/SUMO-specific protease SENP6 , SUMO1/sentrin specific peptidase 6 , SUMO/sentrin specific protease 6 , SUMO/sentrin specific peptidase 6 , Sumo1/sentrin/SMT3 specific peptidase 6 , Sentrin-specific protease 6-like protein
GENE ID | SPECIES |
---|---|
26054 | Homo sapiens |
462829 | Pan troglodytes |
215351 | Mus musculus |
300860 | Rattus norvegicus |
481883 | Canis lupus familiaris |
503939 | Danio rerio |
533853 | Bos taurus |
421859 | Gallus gallus |
100068828 | Equus caballus |
100353104 | Oryctolagus cuniculus |
100155462 | Sus scrofa |
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