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Secreted Epidermal Growth Factor Proteins

Vaccinia growth factor stimulates cellular proliferation (hyperplasia) around infected cells.

Type
  • 4
    Protein
Antigen
  • 4
Reactivity
  • 4
Application
  • 4
Host
  • 4
Binding Specificity
  • 4
Conjugate
  • 4
Protein Type
  • 4
Format
  • 4
4 Products
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityVaccinia Virus (VACV)
Application ELISA
Order details Cat. No. ABIN1651063
$2,119.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityVaccinia Virus (VACV)
Application ELISA
Order details Cat. No. ABIN1593871
$2,119.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityVaccinia Virus (VACV)
Application ELISA
Order details Cat. No. ABIN1677405
$2,119.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityVaccinia Virus (VACV)
Application ELISA
Order details Cat. No. ABIN1660713
$2,119.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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Secreted Epidermal Growth Factor (C11R) Protein Profile

Protein Summary

Vaccinia growth factor stimulates cellular proliferation (hyperplasia) around infected cells. This effect is beneficial for virus replication in vivo, because poxviruses replicate possibly better in proliferating cells than in quiescent cells. Acts by binding host EGFR, inducing its dimerization, autophosphorylation and leading to activation of several cellular pathways regulating cell proliferation or cell survival. The activation by host EFGR of mitogen activated protein kinases (MAPK) and extracellular- signal regulated kinases (ERK) are essential for the positive effect of vaccinia growth factor on poxvirus virulence in vivo.

Gene names and symbols associated with C11R

  • temporal expression: early (C11R) antibody

Protein level used designations for C11R

epidermal growth factor-like protein (EGF-like protein)

GENE ID SPECIES
3707624 Vaccinia virus