anti-Selectin P Ligand (SELPLG) Antibodies

SELPLG encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes.

list all antibodies Gene Name GeneID UniProt
Anti-Human SELPLG SELPLG 6404 Q14242
Anti-Mouse SELPLG SELPLG 20345  
Anti-Rat SELPLG SELPLG 363930  
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Top anti-SELPLG Antibodies at antibodies-online.com

Showing 10 out of 294 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SELPLG Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SELPLG Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rat Un-conjugated CyTOF, ELISA, FACS, IHC, IHC (fro), IHC (p), WB Human peripheral blood lymphocytes stained with purified HECA-452, followed by anti-mouse IgG FITC Flow (Cell Surface): Cutaneous Lymphocyte Antigen (CLA) Antibody (HECA-452) [ABIN2629479] - A cell surface stain was performed on CD14+ hPBMCs with Cutaneous Lymphocyte Antigen (CLA) antibody (HECA-452) ABIN2629479 and a matched isotype control NBP2-31379. Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at room temperature, followed by rat-Dylight 488 conjugated secondary antibody. A co-stain was performed using CD14 antibody ABIN2629478AF488. 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Mouse APC FACS Surface staining of human peripheral blood cells with anti-human CD162 (clone TC2). 100 Tests Log in to see 5 to 7 Days
$366.85
Details
Human Mouse Un-conjugated Func, FACS, WB   100 μg Log in to see 7 to 9 Days
$478.50
Details
Human Rabbit Un-conjugated FACS, WB SELPLG Antibody (C-term)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SELPLG antibody detected the SELPLG protein (arrow). SELPLG Antibody (C-term)  flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB flow cytometric analysis of Jurkat cells using SELPLG Antibody (C-term) Cat.-No AP53840PU-N (Right histogram) compared to a negative control cell (Left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Western blot analysis of SELPLG Antibody (C-term) Cat.-No AP53840PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the SELPLG antibody detected the SELPLG protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated CyTOF, FACS Flow (Cell Surface): PSGL-1/CD162 Antibody (TC2) [NBP1-44599] - Analysis using the PE conjugate of NBP1-44599. Surface staining of human peripheral blood cells with anti-human CD162 (clone TC2). 0.1 mg Log in to see 12 to 15 Days
$415.44
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric adenocarcinoma labeled with Anti-CD162 Polyclonal Antibody, Unconjugated (ABIN679298) followed by conjugation to the secondary antibody Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-CD162 Polyclonal Antibody, Unconjugated (ABIN679298) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details

Top referenced anti-SELPLG Antibodies

  1. Mouse (Murine) Monoclonal SELPLG Primary Antibody for BR, FACS - ABIN1177261 : Borges, Eytner, Moll, Steegmaier, Campbell, Ley, Mossmann, Vestweber: The P-selectin glycoprotein ligand-1 is important for recruitment of neutrophils into inflamed mouse peritoneum. in Blood 1997 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal SELPLG Primary Antibody for CyTOF, ELISA - ABIN262947 : Walcheck, Leppanen, Cummings, Knibbs, Stoolman, Alexander, Mattila, McEver: The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin. in Blood 2002 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal SELPLG Primary Antibody for BR, CyTOF - ABIN5012982 : Santen, Schramm, Menger, Wang, Jeppsson, Thorlacius: P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2008 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal SELPLG Primary Antibody for Func, FACS - ABIN610433 : Connolly, Chait, Duncan, Taylor: CT-guided percutaneous needle biopsy of small lung nodules in children. in Pediatric radiology 1999 (PubMed)
    Show all 3 Pubmed References

  5. Mouse (Murine) Polyclonal SELPLG Primary Antibody for ICC, IHC - ABIN1870024 : Baba, Batanova, Kitoh, Takashima: Adhesion of Toxoplasma gondii tachyzoite-infected vehicle leukocytes to capillary endothelial cells triggers timely parasite egression. in Scientific reports 2017 (PubMed)

  6. Human Monoclonal SELPLG Primary Antibody for CyTOF, FACS - ABIN4348165 : Wake, Mori, Liu, Morioka, Teshigawara, Sakaguchi, Kuroda, Gao, Takahashi, Ohtsuka, Yoshino, Morimatsu, Nishibori: Histidine-Rich Glycoprotein Prevents Septic Lethality through Regulation of Immunothrombosis and Inflammation. in EBioMedicine 2016 (PubMed)

More Antibodies against SELPLG Interaction Partners

Human Selectin P Ligand (SELPLG) interaction partners

  1. The Interaction of Selectins and PSGL-1 as a Key Component in Thrombus Formation and Cancer Progression.

  2. Studies indicate that P-selectin glycoprotein ligand-1 (PSGL-1) PSGL-1 can negatively regulate T cell function.

  3. Results suggest that PSGL-1 may play an oncogenic role in the development of intestinal tumors, and this is likely mediated through activation of NFkB signaling by MIP (show TNPO1 Antibodies)-1g.

  4. c-Myc (show MYC Antibodies) regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection.

  5. The percentage of CXCR3 (show CXCR3 Antibodies)(+) CD4 (show CD4 Antibodies)(+) TEM (show CYLD Antibodies) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA(+) CD4 (show CD4 Antibodies)(+) TCM cells expressing CCR6 (show CCR6 Antibodies)(+) or CCR4 (show CCR4 Antibodies)(+)CXCR3 (show CXCR3 Antibodies)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  6. Platelet-leukocyte aggregations increased in acute ischemic stroke patients rapidly within 3h. The I allele of PSGL-1 M62I was associated with risk of developing acute ischemic stroke, especially large artery atherosclerosis stroke and small artery occlusion stroke. Small artery occlusion stroke patients with the II genotype of PSGL-1 M62I have the higher level of platelet-neutrophil aggregates.

  7. The significant presence of CLA+ T cells and E-selectin (show SELE Antibodies) expressions in the OLPG suggests their involvement in the etiopathogenesis of OLP; however, only a weak correlation between CLA+ T cells and E-selectin (show SELE Antibodies) was observed.

  8. PSGL-1 is a novel receptor for S. pneumoniae that contributes to protection against invasive pneumococcal disease.

  9. This study provides a better understanding of the biology of P-selectin (show SELP Antibodies) and PSGL-1 and their roles in dissemination and resensitization of Multiple myeloma treatment.

  10. Report influence of SELPLG variation on leukocyte-platelet interactions in cardiovascular disease.

Mouse (Murine) Selectin P Ligand (SELPLG) interaction partners

  1. results indicate that P-selectin (show SELP Antibodies) deletion significantly decreases tumor stiffness in Rip1 (show RALBP1 Antibodies)-Tag2 mice by inhibiting LOX (show LOX Antibodies) expression.

  2. this study shows that PSGL-1 plays a fundamental role in balancing viral control and immunopathology and also functions to regulate T cell responses in the tumor microenvironment

  3. Psgl-1 deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (show AKT1 Antibodies) axis.

  4. Circulating soluble P-selectin (show SELP Antibodies) must dimerize to promote inflammation and thrombosis in mice.

  5. The results from the present study suggest that activated platelets secrete Pselectin to promote cardiac inflammation and fibrosis in Ang (show ANG Antibodies) IIinduced hypertension.

  6. These findings indicate a novel pathway in tumor metastasis, i.e., tumor cell mediated activation of P-selectin (show SELP Antibodies) in platelets, followed by activation and secretion of Asm (show SMPD1 Antibodies) and in turn release of ceramide and tumor metastasis. The data suggest that p38 MAPK (show MAPK14 Antibodies) acts downstream from P-selectin (show SELP Antibodies) and is necessary for the secretion of Asm (show SMPD1 Antibodies).

  7. Psgl-1 deficiency is protective against the prothrombotic effects of IL-1beta (show IL1B Antibodies) .

  8. PSGL-1, CD43, and CD44 moved normally to the uropods of chemokine-stimulated C1galt1(-/-) neutrophils

  9. these results demonstrate that P-selectin (show SELP Antibodies) expression on ECs is regulated in part by glycosylation mechanisms and that glycosylation inhibitors efficiently reduce the adhesion of sRBCs and leukocytes to ECs.

  10. endothelial colony-forming cells interact with activated neutrophils via PSGL-1 and L-selectin (show SELL Antibodies)

SELPLG Antigen Profile

Protein Summary

This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with SELPLG

  • selectin P ligand (SELPLG) antibody
  • selectin, platelet (p-selectin) ligand (Selplg) antibody
  • clasper (cla) antibody
  • selectin P ligand (Selplg) antibody
  • CD162 antibody
  • CLA antibody
  • Psgl-1 antibody
  • Psgl1 antibody
  • Selp1 antibody
  • SELPG antibody
  • Selpl antibody
  • SELPLG antibody

Protein level used designations for SELPLG

P-selectin glycoprotein ligand 1 , cutaneous lymphocyte-associated associated antigen , selectin P ligand , P-selectin glycoprotein ligand 1 propeptide , P-selectin glycoprotein ligand-1 , leukocyte cell surface adhesion molecule , selectin, platelet (p-selectin) ligand

GENE ID SPECIES
6404 Homo sapiens
452211 Pan troglodytes
611673 Canis lupus familiaris
617434 Bos taurus
100034025 Equus caballus
100125963 Sus scrofa
20345 Mus musculus
12720 Mus musculus
363930 Rattus norvegicus
100712957 Cavia porcellus
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