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SELPLG antibody (Selectin P Ligand) (APC) Primary Antibody

SELPLG Reactivity: Human FACS Host: Mouse Monoclonal TC2 APC
Catalog No. ABIN609651
$528.26
Plus shipping costs $45.00
100 tests
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Delivery in 5 to 7 Business Days
  • Target
    SELPLG
    Reactivity
    • 96
    • 33
    • 15
    • 1
    • 1
    • 1
    Human
    Host
    • 71
    • 44
    • 12
    Mouse
    Clonality
    • 65
    • 61
    Monoclonal
    Conjugate
    • 41
    • 11
    • 9
    • 8
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SELPLG antibody is conjugated to APC
    Application
    • 90
    • 51
    • 36
    • 30
    • 22
    • 22
    • 16
    • 12
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    The antibody TC2 reacts with CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes, it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.
    Cross-Reactivity (Details)
    Human
    Immunogen
    Human thymocytes
    Clone
    TC2
    Isotype
    IgG1
  • Application Notes
    The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
    Comment

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Reconstitution
    No reconstitution is necessary.
    Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Avoid prolonged exposure to light.
    Storage
    4 °C
    Storage Comment
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Target
    SELPLG
    Alternative Name
    CD162 (SELPLG Antibody Abstract)
    Synonyms
    CD162, CLA, PSGL-1, PSGL1, SELPLG, SELPG, Psgl-1, Psgl1, Selp1, Selpl, selectin P ligand, selectin, platelet (p-selectin) ligand, clasper, SELPLG, Selplg, cla
    Background
    CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.
    Gene ID
    6404
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