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SELPLG antibody (Selectin P Ligand) Primary Antibody

SELPLG Reactivity: Human IHC, StM Host: Mouse Monoclonal PSGL1-1601 unconjugated
Catalog No. ABIN6940571
$494.31
Plus shipping costs $45.00
100 μg ABIN6940571
100 μg ABIN6940571
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  • Target
    SELPLG
    Reactivity
    • 96
    • 33
    • 15
    • 1
    • 1
    • 1
    Human
    Host
    • 71
    • 44
    • 12
    Mouse
    Clonality
    • 65
    • 61
    Monoclonal
    Conjugate
    • 40
    • 11
    • 9
    • 9
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SELPLG antibody is un-conjugated
    Application
    • 91
    • 51
    • 35
    • 30
    • 22
    • 22
    • 16
    • 12
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant human SELPLG (CD162) protein
    Clone
    PSGL1-1601
    Isotype
    IgG1 kappa
  • Application Notes

    Positive Control: Jurkat cells. Tonsil or Spleen.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    SELPLG
    Alternative Name
    SELPLG (SELPLG Antibody Abstract)
    Synonyms
    CD162, CLA, PSGL-1, PSGL1, SELPLG, SELPG, Psgl-1, Psgl1, Selp1, Selpl, selectin P ligand, selectin, platelet (p-selectin) ligand, clasper, SELPLG, Selplg, cla
    Background
    CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
    Molecular Weight
    43-120kDa
    Gene ID
    6404
    UniProt
    Q14242
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