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SRP72 encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). Additionally we are shipping and many more products for this protein.
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Human Polyclonal SRP72 Primary Antibody for ICC, IF - ABIN4355987
Kirwan, Walne, Plagnol, Velangi, Ho, Hossain, Vulliamy, Dokal: Exome sequencing identifies autosomal-dominant SRP72 mutations associated with familial aplasia and myelodysplasia. in American journal of human genetics 2012
This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, signal recognition particle protein 72
, signal recognition particle 72 kDa protein
, signal recognition particle 72kDa
, signal recognition particle subunit Srp72
, part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex
, type II secretory pathway family
, signal recognition particle 72 kDa
, signal recognition particle subunit SRP72
, signal recognition particle,72 kDa subunit