Sirtuin 2 (SIRT2) ELISA Kits

SIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping Sirtuin 2 Antibodies (130) and Sirtuin 2 Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SIRT2 22933 Q8IXJ6
SIRT2 64383 Q8VDQ8
SIRT2 361532 Q5RJQ4
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Top Sirtuin 2 ELISA Kits at antibodies-online.com

Showing 7 out of 29 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.78 pg/mL 3.12-200 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$910.56
Details
Rat 0.66 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Mouse 0.188 ng/mL 0.31 ng/mL - 20 ng/mL   96 Tests Log in to see 13 to 16 Days
$601.54
Details
Mouse 0.61 ng/mL 1.56 ng/mL - 100 ng/mL   96 Tests Log in to see 15 to 17 Days
$832.83
Details
Mammalian
100 Tests Log in to see 2 to 3 Days
$495.00
Details
Please inquire
1 kit Log in to see 2 to 3 Days
$624.00
Details
Please inquire
1 kit Log in to see 2 to 3 Days
$624.00
Details

More ELISA Kits for Sirtuin 2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Sirtuin 2 (SIRT2) interaction partners

  1. Sirt2 has an role in the regulation of mitochondrial energy metabolism.

Arabidopsis thaliana Sirtuin 2 (SIRT2) interaction partners

  1. SRT2 is important in fine-tuning mitochondrial energy metabolism.

  2. AtSRT2 is a deacetylase that negatively regulates the plant basal defense and PR1 expression.

Human Sirtuin 2 (SIRT2) interaction partners

  1. Data suggest that inhibition of sirtuin 1 and sirtuin 2 in hepatocellular carcinoma cells (a) impairs cell survival and cell migration and (b) down-regulates expression of P-glycoprotein and MRP3 (ATP binding cassette subfamily C member 3).

  2. SIRT2 inhibition may improve microtubule assembly thus representing a valid approach as disease-modifying therapy for Alzheimer's disease.

  3. Data show that single nucleotide polymorphism rs2015C in sirtuin 2 protein (SIRT2) gene 3'-UTR (show UTS2R ELISA Kits) was significantly associated with increased risk of colorectal cancer (CRC (show CALR ELISA Kits)).

  4. Authors show that SIRT2 is downregulated in insulin (show INS ELISA Kits)-resistant hepatocytes and livers, and this was accompanied by increased generation of reactive oxygen species, activation of stress-sensitive ERK1/2 (show MAPK1/3 ELISA Kits) kinase, and mitochondrial dysfunction.

  5. Those findings highlight the potential role of SIRT2 in HBV and HBV-mediated HCC by interaction with HBx.

  6. The SIRT2 functions as a mitochondrial sirtuin (show SIRT1 ELISA Kits), as well as a regulator of autophagy/mitophagy to maintain mitochondrial biology, thus facilitating cell survival.

  7. increased expression of SRF that was observed in the aged heart may affect SIRT2 gene expression and contribute to altered metabolic status in senescence

  8. SIRT2 and RIPK1 (show RIPK1 ELISA Kits) were localized to the syncytiotrophoblast, villous leukocytes and vasculature in all preterm placentas. A significant reduction in SIRT2 protein expression in both preeclampsia and fetal growth restricted placentas was identified. Immunofluorescence identified both SIRT2 and RIPK1 (show RIPK1 ELISA Kits) in the cytotrophoblast cytoplasm.

  9. mutations in sirtuin2 increase the stability of the conserved catalytic sirtuin (show SIRT1 ELISA Kits) domain, thereby increasing the catalytic efficiency of the mutant enzymes.

  10. targeting SIRT2 may be a rational strategy for diminishing Slug abundance and its associated malignant traits in basal-like breast cancer.

Cow (Bovine) Sirtuin 2 (SIRT2) interaction partners

  1. The results indicate that the variations in the class I sirtuin (show SIRT1 ELISA Kits) genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  2. An association analysis showed that the two loci of SIRT2 were significantly correlated with some body size traits and the H2H2 (-CT-CT (show CALCA ELISA Kits)-) diplotypes performed better than other combinations.

  3. Data suggest that the silent information regulator 2 (SIRT2) gene may be a candidate gene for marker-assisted selection in the development of breeding programs for Qinchuan cattle.

Mouse (Murine) Sirtuin 2 (SIRT2) interaction partners

  1. SIRT2 knockout mice show marked up-regulation in AMPAR acetylation and protein accumulation, aberrant synaptic plasticity and impaired memory.

  2. SIRT2 inhibition may improve microtubule assembly thus representing a valid approach as disease-modifying therapy for Alzheimer's disease.

  3. Authors show that SIRT2 is downregulated in insulin (show INS ELISA Kits)-resistant hepatocytes and livers, and this was accompanied by increased generation of reactive oxygen species, activation of stress-sensitive ERK1/2 (show MAPK1/3 ELISA Kits) kinase, and mitochondrial dysfunction.

  4. Given the significance of KRAS activity as a driver in tumorigenesis, identification of K147 acetylation as a novel post-translational modification directed by SIRT2 in vivo may provide a better understanding of the mechanistic link regarding the crosstalk between non-genetic and genetic factors in KRAS driven tumors.

  5. SIRT2 modulates microvascular inflammation in sepsis and affects survival

  6. This study showed that Sirt2-dependent GKRP (show GCKR ELISA Kits) deacetylation improves impaired HGU and suggest that it may be a therapeutic target for type 2 diabetes.

  7. AMPK (show PRKAA1 ELISA Kits) and Sirt2 control compensatory glucose uptake in metabolically arrested mitochondria.

  8. SIRT2 promotes AMPK (show PRKAA1 ELISA Kits) activation by deacetylating the kinase LKB1 (show STK11 ELISA Kits). Loss of SIRT2 reduces AMPK (show PRKAA1 ELISA Kits) activation, promotes aging-related and Ang II (show AGT ELISA Kits)-induced cardiac hypertrophy, and blunts metformin-mediated cardioprotective effects.

  9. found a decreased ratio of dopaminergic neurons in primary midbrain cultures treated with the SIRT2 inhibitor AK-7

  10. mitochondrial dysfunction triggers LKB1 (show STK11 ELISA Kits)-mediated AMPK (show PRKAA1 ELISA Kits) activation, which stimulates Sirt2 phosphorylation, leading to activation of mTOR (show FRAP1 ELISA Kits)-RAPTOR (show RPTOR ELISA Kits) and Glut1 (show SLC2A1 ELISA Kits)-mediated glucose uptake.

Sirtuin 2 (SIRT2) Antigen Profile

Antigen Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.

Gene names and symbols associated with Sirtuin 2 (SIRT2) ELISA Kits

  • Sirtuin 2 (Sirt2) antibody
  • sirtuin 2 (SIRT2) antibody
  • sirtuin 2 S homeolog (sirt2.S) antibody
  • NAD-dependent deacetylase sirtuin 2 homolog (Sirt2) antibody
  • sirtuin 2 (SRT2) antibody
  • sirtuin 2 (sirt2) antibody
  • sirtuin 2 (Sirt2) antibody
  • sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) (sirt2) antibody
  • 5730427M03Rik antibody
  • AtSRT2 antibody
  • BmSirt2 antibody
  • CG5085 antibody
  • D.mel2 antibody
  • Dmel\\CG5085 antibody
  • dSIRT2 antibody
  • SIR2 antibody
  • Sir2l antibody
  • SIR2L2 antibody
  • Sirt2 antibody
  • sirtuin 2 antibody
  • T2K12.8 antibody
  • wu:fb57d05 antibody
  • zgc:55966 antibody
  • zgc:77003 antibody

Protein level used designations for Sirtuin 2 (SIRT2) ELISA Kits

CG5085-PA , Sirt2-PA , sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) , sirtuin 2 , NAD-dependent deacetylase SIRT2 , NAD-dependent deacetylase sirtuin-2 , histone NADC , silent information regulator 2 , nicotinamide adenine dinucleotide-dependent histone deacetylase , NAD-dependent deacetylase sirtuin 2 homolog , NAD-dependent protein deacetylase sirtuin-2 , SIR2-like protein 2 , regulatory protein SIR2 homolog 2 , sir2-related protein type 2 , sirtuin type 2 , sirtuin-like protein 2 , mSIR2L2 , silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2 , 5E5 antigen

GENE ID SPECIES
42414 Drosophila melanogaster
456013 Pan troglodytes
495688 Xenopus laevis
548628 Gallus gallus
612558 Canis lupus familiaris
692483 Bombyx mori
830782 Arabidopsis thaliana
100380582 Salmo salar
22933 Homo sapiens
100125964 Sus scrofa
504463 Bos taurus
64383 Mus musculus
361532 Rattus norvegicus
100172430 Pongo abelii
322309 Danio rerio
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