Protein Summary

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.

Gene names and symbols associated with SCN7A

• sodium channel, voltage-gated, type VII, alpha (Scn7a) antibody
• sodium voltage-gated channel alpha subunit 7 (Scn7a) antibody
• sodium voltage-gated channel alpha subunit 7 (SCN7A) antibody

• 1110034K09Rik antibody
• AI642000 antibody
• Na-G antibody
• NaG antibody
• Nav2 antibody
• Show all synonym aliases
• Nav2.1 antibody
• Nav2.2 antibody
• Nav2.3 antibody
• Nax antibody
• SCN6A antibody

Protein level used designations for SCN7A

sodium channel, voltage-gated, type VI, alpha polypeptide , sodium channel, voltage-gated, type VII, alpha polypeptide , sodium channel protein type 7 subunit alpha , sodium channel voltage-gated type VI alpha polypeptide , sodium channel, voltage-gated, type 6, alpha polypeptide , putative voltage-gated sodium channel subunit alpha Nax , sodium channel protein cardiac and skeletal muscle subunit alpha , sodium channel protein type VII subunit alpha , voltage-dependent sodium channel alpha subunit