anti-Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Antibodies

SCN7A encodes one of the many voltage-gated sodium channel proteins. Additionally we are shipping Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Kits (7) and Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCN7A 20272  
SCN7A 64155  
SCN7A 6332 Q01118
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Top anti-Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Antibodies at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  SCN7A  Sample Type:  Fetal Thymus lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using SCN7A Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using SCN7A antibody. Western blot analysis of extracts of various cell lines, using SCN7A antibody (ABIN4905098) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of human lymph node with SCN7A polyclonal antibody  shows strong nuclear positivity in reaction center cells at 1:50-1:200 dilution. 100 μL Log in to see 11 to 12 Days
$577.33
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat stomach labeled with Anti-SCN7A Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.2 mL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Cy7 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details

Top referenced anti-Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Antibodies

  1. Human Polyclonal SCN7A Primary Antibody for ELISA, WB - ABIN565642 : Maksimova, Hara, Nikolaeva, Chun-Feng, Usui, Takagi, Nishihira, Miyashita, Fujiwara, Oyama, Nogovicina, Sukhomyasova, Potapova, Kuwano, Takahashi, Nishizawa, Onodera: Neuroblastoma amplified sequence gene is associated with a novel short stature syndrome characterised by optic nerve atrophy and Pelger-Huët anomaly. in Journal of medical genetics 2010 (PubMed)

More Antibodies against Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Interaction Partners

Mouse (Murine) Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) interaction partners

  1. These results suggest that the Na(+) signal generated in Nax-positive glial cells leads to the activation of TRPV4-positive neurons in sCVOs to stimulate water intake by using EETs as gliotransmitters.

  2. SAP97 promotes the stability of Nax channels at the plasma membrane.

  3. Nax/Nav2 channel is expressed in alveolar type II cells, suggesting a role in the control of extracellular sodium level.

  4. Nav2-deficient mice show a preference for 0.15 M NaCl over water during a free two-choice intake test compared with wild-type; preference ratios for NaCl in wild tend to increase after combined superior laryngeal and glossopharyngeal nerve transection.

  5. Results show that the subfornical organ is the center of the control of salt-intake behavior in the brain, where the Na-level-sensitive Na(x) channel is involved in sensing the physiological increase in the Na level of body fluids.

  6. results suggest that glial cells bearing the Na(x) channel are the first to sense a physiological increase in the level of sodium in the body fluid.

  7. identified the promoter and transcription start sites of Na(x) sodium channel in dorsal root ganglia neurons; findings provide the basis with which to understand tissue-specific regulation of Nax sodium channel gene (Scn7a) expression

Human Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) interaction partners

  1. The authors demonstrated that the sodium channel Nax functions as a sodium sensor. With increased extracellular sodium, Nax up-regulates prostasin, which results in activation of the sodium channel ENaC.

  2. SNP rs7565062 of SCN7A was significantly associated with essential hypertension in a Northern Han Chinese population

Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Antigen Profile

Protein Summary

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.

Gene names and symbols associated with SCN7A

  • sodium channel, voltage-gated, type VII, alpha (Scn7a) antibody
  • sodium voltage-gated channel alpha subunit 7 (Scn7a) antibody
  • sodium voltage-gated channel alpha subunit 7 (SCN7A) antibody
  • 1110034K09Rik antibody
  • AI642000 antibody
  • Na-G antibody
  • NaG antibody
  • Nav2 antibody
  • Nav2.1 antibody
  • Nav2.2 antibody
  • Nav2.3 antibody
  • Nax antibody
  • SCN6A antibody

Protein level used designations for SCN7A

sodium channel, voltage-gated, type VI, alpha polypeptide , sodium channel, voltage-gated, type VII, alpha polypeptide , sodium channel protein type 7 subunit alpha , sodium channel voltage-gated type VI alpha polypeptide , sodium channel, voltage-gated, type 6, alpha polypeptide , putative voltage-gated sodium channel subunit alpha Nax , sodium channel protein cardiac and skeletal muscle subunit alpha , sodium channel protein type VII subunit alpha , voltage-dependent sodium channel alpha subunit

GENE ID SPECIES
20272 Mus musculus
64155 Rattus norvegicus
6332 Homo sapiens
100516881 Sus scrofa
507516 Bos taurus
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