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SCN7A Products

(Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

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This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011].

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Featured SCN7A Categories

SCN7A Antibodies

High quality antibodies with extensive validation data.

SCN7A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SCN7A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (3)
Cat. No. ABIN7169925
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7184122
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
  • (1)
Cat. No. ABIN1386696
Quantity 100 μL
Datasheet Datasheet

Recommended SCN7A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3076698
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3076694
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3076695
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SCN7A products

Gorter, Zurolo, Iyer, Fluiter, van Vliet, Baayen, Aronica: "Induction of sodium channel Na(x) (SCN7A) expression in rat and human hippocampus in temporal lobe epilepsy." in: Epilepsia, Vol. 51, Issue 9, pp. 1791-800, (2010) (PubMed).

Synonyms and alternative names related to SCN7A

sodium channel, voltage-gated, type VII, alpha (Scn7a), sodium voltage-gated channel alpha subunit 7 (Scn7a), sodium voltage-gated channel alpha subunit 7 (SCN7A), 1110034K09Rik, AI642000, Na-G, NaG, Nav2, Nav2.1, Nav2.2, Nav2.3, Nax, Scn6a, SCN6A

Protein level used designations for SCN7A

  • sodium channel, voltage-gated, type VI, alpha polypeptide
  • sodium channel, voltage-gated, type VII, alpha polypeptide
  • sodium channel protein type 7 subunit alpha
  • sodium channel voltage-gated type VI alpha polypeptide
  • sodium channel, voltage-gated, type 6, alpha polypeptide
  • putative voltage-gated sodium channel subunit alpha Nax
  • sodium channel protein cardiac and skeletal muscle subunit alpha
  • sodium channel protein type VII subunit alpha
  • voltage-dependent sodium channel alpha subunit
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