anti-Solute Carrier Family 22 (Organic Cation Transporter), Member 11 (SLC22A11) Antibodies

The protein encoded by SLC22A11 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. Additionally we are shipping SLC22A11 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC22A11 55867 Q9NSA0
SLC22A11    
SLC22A11    
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Top anti-SLC22A11 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Dog Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  SLC22A11  Sample Type:  Human Adult Placenta  Antibody Dilution:  1.0ug/ml Host:  Rabbit  Target Name:  SLC22A11  Sample Type:  Human Fetal Heart  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SLC22A11 Antibody Titration:  1.25ug/ml  Positive Control:  Transfected 293T 100 μL 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cells, using SLC22A11 antibody. Immunofluorescence analysis of A549 cell using SLC22A11 antibody. Blue: DAPI for nuclear staining. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL 11 to 14 Days
$1,079.83
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of extracts of various cell lines, using SLC22A11 antibody. Immunofluorescence analysis of A549 cells using SLC22A11 antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IF/ICC, WB 100 μL 11 to 18 Days
$383.76
Details
Human Rabbit Un-conjugated IF/ICC, WB Western blot analysis of extracts of various cell lines, using SLC22A11 antibody (ABIN5975730) at 1/1000 dilution. Immunofluorescence analysis of A549 cells using SLC22A11 antibody (ABIN5975730). Blue: DAPI for nuclear staining. 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg 11 to 14 Days
$1,123.83
Details

Top referenced anti-SLC22A11 Antibodies

  1. Human Polyclonal SLC22A11 Primary Antibody for IHC (fro) - ABIN548995 : Cha, Sekine, Kusuhara, Yu, Kim, Kim, Sugiyama, Kanai, Endou: Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 Pubmed References

  2. Dog (Canine) Polyclonal SLC22A11 Primary Antibody for WB - ABIN2781664 : Carballo, Johnson, Sedgwick, Cha: Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination. in Cell 2008 (PubMed)

More Antibodies against SLC22A11 Interaction Partners

Human Solute Carrier Family 22 (Organic Cation Transporter), Member 11 (SLC22A11) interaction partners

  1. The first genome-wide association study for serum uric acid level in Indians revealed association of SLC2A9, SLC22A11 and ABCG2 gene variants at genome wide significance level in Type 2 diabetes patients.

  2. modifies placental passage of perfluorinated alkyl acids, may decrease fetal exposure

  3. The regulation of hOAT4 activity was mediated by sgk2 acting through Nedd4-2.

  4. SLC22A11 at the basal plasma membrane of human placental syncytiotrophoblasts plays a predominant role in the uptake of 16alpha-OH DHEAS for placental estriol synthesis.

  5. A common variant of OAT4/SLC22A11 is associated with renal underexcretion type gout in Japanese men.

  6. Our analysis provides evidence for multiple ancestral-specific effects across the SLC22A11/SLC22A12 locus that presumably influence the activity of OAT4 and URAT1 and risk of gout.

  7. When investigating the genes separately, SLC22A11 and SLC2A9 showed a significant interaction, consistent with the former encoding an organic anion/dicarboxylate exchanger, which mediates diuretic transport in the kidney.

  8. Genetic variants of human organic anion transporter 4 demonstrate altered transport of endogenous substrates.

  9. The down-regulation of hOAT4 activity by activation of protein kinase C and the up-regulation of hOAT4 activity by NHERF-1 are mediated through alteration of hOAT4 internalization.

  10. Several naturally occurring SNPs encode variant hOAT4s that may impair the renal tubular re-absorption of important drug substrates.

  11. elucidation of the molecular mechanism for renal tetracycline transport by human organic anion transporters (hOATs) using proximal tubular cells stably expressing hOATs

  12. Glycosylation serves as a means to specifically regulate hOAT4 function in vivo.

  13. hOAT4 is the long-postulated, low-affinity apical urate anion exchanger that facilitates hydrochlorothiazide-associated hyperuricemia.

  14. The interaction of PDZ proteins with hOAT4 may be cell-specific. In placenta, a different set of interacting proteins from PDZK1 and NHERF1 may be required to modulate hOAT4 activity.

  15. The present study demonstrates that hOAT4 variants can causing inter-individual variation in anionic drug uptake and, therefore, could be used as markers for certain diseases including osteoporosis.

  16. Findings suggest that hOAT4 and caveolin-1 share a cellular expression in the plasma membrane and caveolin-1 up-regulates the organic anionic compound uptake by hOAT4 under the normal physiological condition.

SLC22A11 Antigen Profile

Protein Summary

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus.

Gene names and symbols associated with SLC22A11

  • solute carrier family 22 member 11 (SLC22A11) antibody
  • solute carrier family 22 member 24 (LOC100349650) antibody
  • DKFZp469L1732 antibody
  • hOAT4 antibody
  • OAT4 antibody

Protein level used designations for SLC22A11

solute carrier family 22 (organic anion/urate transporter), member 11 , solute carrier family 22 member 11 , solute carrier family 22 (organic anion/cation transporter), member 11 , organic anion transporter 4

GENE ID SPECIES
466654 Pan troglodytes
699212 Macaca mulatta
100174235 Pongo abelii
100349650 Oryctolagus cuniculus
55867 Homo sapiens
518926 Bos taurus
612103 Canis lupus familiaris
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