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SLC6A2 encodes a member of the sodium symporter family. Additionally we are shipping SLC6A2 Kits (25) and SLC6A2 Proteins (3) and many more products for this protein.
Showing 10 out of 39 products:
Human Polyclonal SLC6A2 Primary Antibody for CM, ICC - ABIN2746956
Wersinger, Jeannotte, Sidhu: Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein. in The European journal of neuroscience 2007
Show all 2 Pubmed References
Cow (Bovine) Polyclonal SLC6A2 Primary Antibody for WB - ABIN2777051
Suzuki, Matsumoto, Oshino, Kamata, Goto, Otani: Combination of the serotonin transporter and norepinephrine transporter gene promoter polymorphisms might influence harm avoidance and novelty seeking in healthy females. in Neuroscience letters 2008
Show all 2 Pubmed References
Mouse (Murine) Monoclonal SLC6A2 Primary Antibody for WB - ABIN447416
Klimek, Stockmeier, Overholser, Meltzer, Kalka, Dilley, Ordway: Reduced levels of norepinephrine transporters in the locus coeruleus in major depression. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1997
T allele of the SNP rs7194256 in the 3'UTR (show UTS2R Antibodies) of the NET gene is more prevalent in diseases where NET impairment is evident, including essential hypertension, depression, panic disorder and postural orthostatic tachycardia syndrome; mechanism involved may include the creation of a binding site for the miRNA miR (show MLXIP Antibodies)-19-3p, which is, at least in part, regulated by circulating norepinephrine concentrations
Polymorphisms of COMT (show COMT Antibodies) (c.649G>A), MAO-A (show MAOA Antibodies) (c.1460C>T), NET (c.1287G>A) Genes and the Level of Catecholamines, Serotonin in Patients with Parkinson's Disease
NET undergoes extensive constitutive internalization and internalized NET mainly is sorted to Rab11-positive recycling endosomes.
In Major Depressive Disorder patients there seems to be a relationship between the volume of the dorsolateral prefrontal cortex and polymorphism of the SLC6A2 G1287A gene.
This corticotropin releasing factor (show CRH Antibodies)-induced regulation on norepinephrine transporter expression and function may play a role in development of stress-related depression and anxiety
a NET 182C and 5-HTTLPR (show SLC6A4 Antibodies) polymorphism interaction is associated with susceptibility to treatment resistant depression and ECT treatment response in antidepressant resistant depression patients
NET gene variants are not involved in the etiology of recurrent major depressive disorder in Chinese Han population.
A Cox (show COX8A Antibodies) regression analysis for remission incidence during the 8-week treatment course significantly depends on SLC6A2 variants (rs28386840, rs40434, and rs187714)from major depression after venlafaxine treatment.
The response to venlafaxine was assessed after 4 weeks of treatment and correlated to serum concentration and functional variants in genes encoding SLC6A2 and SLC6A4 (show SLC6A4 Antibodies)
polymorphisms of 1287G/A, -182T/C and -3081A/T in the norepinephrine transporter gene are not risk factors in alcohol dependence.
Findings suggest that a combination of forward and reverse EphB1 (show EPHB1 Antibodies)/2 receptor-mediated signaling contribute to posterior branch of the anterior commissure and corpus callosum axon guidance
During re-epithelialization ephrin-B1 (show EFNB1 Antibodies) and its receptor EphB2 (show EPHB2 Antibodies) are both upregulated in vivo, just for the duration of repair.
Differences in gene expression in the mouse frontal cortex with life-long norepinephrine transporter knock-out were studied using a whole-genome microarray approach
In a genetic medulloblastoma model, EphB1 (show EPHB1 Antibodies) knockout resulted in a significant delay in tumor recurrence following irradiation compared to EphB1 (show EPHB1 Antibodies)-expressing control tumors.
inhibition of p38 MAPK (show MAPK14 Antibodies) or the manipulation of NET-Thr (show TRH Antibodies)(30) motif/phosphorylation via a TAT (show TAT Antibodies) peptide strategy prevents cocaine-induced NET up-regulation, locomotor sensitization, and conditioned place preference
this is the first report which suggests the beneficial effect of modulation of TRPV1 (show TRPV1 Antibodies) receptors and NET in Chronic cerebral hypoperfusion vascular dementia
EphB1 (show EPHB1 Antibodies) expression is activated in the spinal cord in a bone cancer model.
The studies introduce EphB1 (show EPHB1 Antibodies) as a new venous-restricted marker in a tissue-specific and time-dependent manner.
Reelin (show RELN Antibodies) induces EphB activation.
role of EphB1 (show EPHB1 Antibodies) receptors signalling in models of inflammatory and neuropathic pain
This gene encodes a member of the sodium symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
, norepinephrine transporter
, sodium-dependent noradrenaline transporter
, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
, solute carrier family 6 member 5
, NE transporter
, solute carrier family 6 member 2
, NaCl-dependent norepinephrine transporter
, neurotransmitter transporter, noradrenal
, transmembrane region 4..26 transmembrane region 55..77 transmembrane region 105..123 transmembrane region 136..157
, norepinephrine plasma membrane transporter
, pulmonary norepinephrine plasma membrane transporter
, sodium-dependent noradrenaline transporter-like
, sodium- and chloride-dependent glycine transporter 2-like
, solute carrier family 6 (neurotransmitter transporter, glycine), member 5