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SLC6A2 Products

(Solute Carrier Family 6 (Neurotransmitter Transporter, Noradrenalin), Member 2 (SLC6A2))
This gene encodes a member of the sodium symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010].

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Featured SLC6A2 Categories

SLC6A2 Antibodies

High quality antibodies with extensive validation data.

SLC6A2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLC6A2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC6A2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
  • (7)
Cat. No. ABIN2777051
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2628420
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6745483
Quantity 100 μL
Datasheet Datasheet

Recommended SLC6A2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970353
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959615
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959616
Quantity 96 tests
Datasheet Datasheet

Recommended SLC6A2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3113227
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131897
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413358
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SLC6A2 products

Li, Ma, Zhao, Li, Zhou, Du: "Extended Contact Lens Wear Promotes Corneal Norepinephrine Secretion and Pseudomonas aeruginosa Infection in Mice." in: Investigative ophthalmology & visual science, Vol. 61, Issue 4, pp. 17, (2020) (PubMed).

Bayles, Harikrishnan, Lambert, Baker, Agrotis, Guo, Jowett, Esler, Lambert, El-Osta: "Epigenetic modification of the norepinephrine transporter gene in postural tachycardia syndrome." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 8, pp. 1910-6, (2012) (PubMed).

Clements, Jamali: "Norepinephrine transporter is involved in down-regulation of beta1-adrenergic receptors caused by adjuvant arthritis." in: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques, Vol. 12, Issue 3, pp. 337-45, (2010) (PubMed).

Suzuki, Matsumoto, Oshino, Kamata, Goto, Otani: "Combination of the serotonin transporter and norepinephrine transporter gene promoter polymorphisms might influence harm avoidance and novelty seeking in healthy females." in: Neuroscience letters, Vol. 439, Issue 1, pp. 52-5, (2008) (PubMed).

Wersinger, Jeannotte, Sidhu: "Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein." in: The European journal of neuroscience, Vol. 24, Issue 11, pp. 3141-52, (2007) (PubMed).

Klimek, Stockmeier, Overholser, Meltzer, Kalka, Dilley, Ordway: "Reduced levels of norepinephrine transporters in the locus coeruleus in major depression." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 21, pp. 8451-8, (1997) (PubMed).

Synonyms and alternative names related to SLC6A2

solute carrier family 6 member 2 (SLC6A2), solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (Slc6a2), solute carrier family 6 member 2 (Slc6a2), solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (SLC6A2), solute carrier family 6 member 5 (SLC6A5), NAT1, NE-T, NET, Net, NET1, SLC6A2, SLC6A5, Slc6a5

Protein level used designations for SLC6A2

  • neurotransmitter transporter
  • norepinephrine transporter
  • sodium-dependent noradrenaline transporter
  • solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • solute carrier family 6 member 5
  • NE transporter
  • solute carrier family 6 member 2
  • NaCl-dependent norepinephrine transporter
  • neurotransmitter transporter, noradrenal
  • transmembrane region 4..26 transmembrane region 55..77 transmembrane region 105..123 transmembrane region 136..157
  • NET
  • norepinephrine plasma membrane transporter
  • pulmonary norepinephrine plasma membrane transporter
  • sodium-dependent noradrenaline transporter-like
  • sodium- and chloride-dependent glycine transporter 2-like
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 5
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