anti-Solute Carrier Organic Anion Transporter Family, Member 1B3 (SLCO1B3) Antibodies

SLCO1B3 encodes a liver-specific member of the organic anion transporter family. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLCO1B3 28234 Q9NPD5
SLCO1B3    
SLCO1B3    
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Top anti-SLCO1B3 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA ABIN570800 (1µg/ml) staining of HEK293 (A) and A431 (B) cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. ABIN570800 Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing membrane staining. The nuclear stain is DAPI (blue 100 μg 6 to 7 Days
$429.84
Details
Human Goat Un-conjugated ELISA   0.1 mg 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB Western Blot at 1:2000 dilution Lane 1: NCI-H460 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 ug per lane. Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: SW480 whole cell lysate Lysates/proteins at 20 ug per lane. 400 μL 2 to 3 Days
$515.63
Details
Human Goat Un-conjugated ELISA   100 μg 11 to 14 Days
$610.50
Details
Human Mouse Un-conjugated ICC, IHC, WB   5 mL 11 to 14 Days
$683.83
Details
Human Rabbit Un-conjugated IF, IHC (p) Immunofluorescent staining of human cell line A-431 with SLCO1B3 polyclonal antibody at 1-4 ug/mL dilution shows positivity in cytoplasm. Immunohistochemical staining of human liver with SLCO1B3 polyclonal antibody shows strong membranous positivity in hepatocytes. 100 μL 11 to 12 Days
$577.33
Details
Human Goat APC ELISA   100 μL 16 Days
$653.71
Details
Human Goat Alkaline Phosphatase (AP) ELISA   100 μL 16 Days
$653.71
Details
Human Goat Biotin ELISA   100 μL 16 Days
$653.71
Details
Human Goat FITC ELISA   100 μL 16 Days
$653.71
Details

Top referenced anti-SLCO1B3 Antibodies

  1. Human Monoclonal SLCO1B3 Primary Antibody for ICC, IF - ABIN261578 : Cui, König, Nies, Pfannschmidt, Hergt, Franke, Alt, Moll, Keppler: Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma. in Laboratory investigation; a journal of technical methods and pathology 2003 (PubMed)
    Show all 13 Pubmed References

  2. Human Polyclonal SLCO1B3 Primary Antibody for ICC, IF - ABIN4341271 : Sun, Furihata, Ishii, Nagai, Harada, Shimozato, Kamijo, Motohashi, Yoshino, Kamiichi, Kobayashi, Chiba: Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers. in Clinical and translational medicine 2015 (PubMed)
    Show all 2 Pubmed References

More Antibodies against SLCO1B3 Interaction Partners

Human Solute Carrier Organic Anion Transporter Family, Member 1B3 (SLCO1B3) interaction partners

  1. OATP1B1- and 1B3-transfected cells could selectively uptake UDCA acyl glucuronide, but not UDCA, OCA, and OCA acyl glucuronide. In summary, the liver disposition of OCA is different from that of UDCA due to hepatic uptake.

  2. G45 and F555 in transmembrane domains 1 and 10 are the most important amino acid residues for OATP1B3 activation.

  3. The authors show that human OATP1B1, 1B3 and 2B1 proteins transport a series of commercially available viability dyes that are generally believed to be impermeable to intact cells.

  4. Two novel genes, SLC15A2 (rs1143671 and rs1143672) and SLCO1B3 (rs4149117 and rs7311358), are associated with the warfarin maintenance dose in a Chinese population.

  5. For the first time, liver-type-OATP1B3 mRNA was detected in ovarian, prostate, bladder and breast cancers.

  6. Organic anion-transporting polypeptide 1B3 as a dual reporter gene for fluorescence and magnetic resonance imaging.

  7. When including the expression levels of SLCO1B3 in intraoperatively examined lymph nodes, 8 factors were found able to predict the prognosis of patients with carcinomas of the cecum and ascending colon. As regards the surgical therapeutic strategies, the resection of >15 local lymph nodes is appropriate for improving the prognosis of patients.

  8. Ct-OATP1B3 mRNA exists in extracellular vesicles and can be detected in (at least) mouse serum, strengthen the potential use of Ct-OATP1B3 mRNA as a serum-based Colorectal Cancer biomarker

  9. It shows high expression of OATP1B3 mRNA in human pancreatic islets, and a high association of OATP1B3 immunostaining with glucagon-producing pancreatic alpha cells.

  10. This study suggests that de novo OATP1B3 expression in prostate cancer drives greater androgen uptake and is consistent with previous observations that greater OATP1B3 activity results in the development of androgen deprivation therapy resistance and shorter overall survival

  11. rs4149117 had no association with hypoglycaemia. The rs4149117 mutation in the SLCO1B3 gene is not associated with sulfonylurea efficacy.

  12. Patients homozygous for the variant allele had significantly higher average E1C plasma concentrations than did other patients. Furthermore, three other SLCO1B1 SNPs, not in LD with rs4149056, were associated with both E1C concentrations and the E1C/E1 ratio and were cis-eQTLs for SLCO1B3.

  13. Data suggest that OATP1B1, OATP1B3, and OATP2B1 participate in transport of perfluoroalkyl acids in hepatocytes; environmental pollutants transported include PFBS (perfluorobutane sulfonate), PFHxS (perfluorohexane sulfonate), and PFOS (perfluorooctane sulfonate).

  14. OATP1B3 protein expression starts at a very high expression level throughout the neonatal phase, thereafter declining in the early childhood years. Then protein expression starts to increase again during the preadolescent period.

  15. High transcript levels of OATP1B3, but not OATP1B1 were observed in isolated human adult islets. While OATP1B3 protein expression was variable, the carrier co-localized more frequently with glucagon-positive alpha cells than insulin-positive beta cells in islets of normal pancreatic tissues from ten subjects using dual immunostaining.

  16. the current studies for the first time report ubiquitination of OATP1B1 and OATP1B3 and the apparent substrate-dependent inhibitory effect of bortezomib on OATP1B3-mediated transport. The data suggest that bortezomib has a low risk of causing OATP-mediated DDIs

  17. Study showed that the multi-specific liver transporter OATP1B3 can form homo-oligomers and can interact with other transporters in the liver, including OATP1B1 and NTCP. We also demonstrated that the homo-oligomers work as two or more individual functional subunits.

  18. Our results did not indicate a strong association between OATP1B1 or OATP1B3 inhibition and hyperbilirubinemia

  19. demonstrate that the N-terminal region is important for the membrane localization of the OATP1B subfamily members and should facilitate future investigations of the mechanisms involved in the regulation and membrane trafficking of these important transporter proteins

  20. SLCO1B3 was significantly downregulated in docetaxel-resistant patient-derived prostatic tumours xenografted into mice. SLCO1B3 determines intracellular concentrations of docetaxel and cabazitaxel and consequently influences taxane efficacy. Loss of the drug transporter SLCO1B3 may drive taxane resistance in prostate cancer.

SLCO1B3 Antigen Profile

Protein Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia.

Gene names and symbols associated with SLCO1B3

  • solute carrier organic anion transporter family member 1B3 (SLCO1B3) antibody
  • solute carrier organic anion transporter family member 1B3 (slco1b3) antibody
  • solute carrier organic anion transporter family member 1B3 (LOC100068155) antibody
  • HBLRR antibody
  • LST-2 antibody
  • LST-3TM13 antibody
  • LST3 antibody
  • MGC108027 antibody
  • OATP-8 antibody
  • OATP1B3 antibody
  • oatp8 antibody
  • OATPC antibody
  • slc21a8 antibody
  • Slc21a10 antibody
  • SLCO1B4 antibody

Protein level used designations for SLCO1B3

liver-specific organic anion transporter 2 , liver-specific organic anion transporter 3TM13 , organic anion transporter 8 , organic anion transporter LST-3c , organic anion-transporting polypeptide 8 , solute carrier family 21 (organic anion transporter), member 8 , solute carrier organic anion transporter family member 1B3 , organic anion transporting polypeptide C , organic anion transporting polypeptide 1b4 , solute carrier organic anion transporter family, member 1B3 , organic anion transporting polypeptide 1b3 , solute carrier organic anion transporter family member 1B3-like

GENE ID SPECIES
28234 Homo sapiens
403519 Canis lupus familiaris
404160 Bos taurus
418187 Gallus gallus
574354 Macaca mulatta
613085 Xenopus (Silurana) tropicalis
100342119 Oryctolagus cuniculus
100404555 Callithrix jacchus
100481529 Ailuropoda melanoleuca
100068155 Equus caballus
100584491 Nomascus leucogenys
100620829 Sus scrofa
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