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SPG7 encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Additionally we are shipping SPG7 Antibodies (77) and many more products for this protein.
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This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7.
, spastic paraplegia 7
, spastic paraplegia 7 homolog
, spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)
, cell adhesion regulator
, cell matrix adhesion regulator
, spastic paraplegia 7 protein