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SPAM1 Proteins

Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes.

10 results:

Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-490) protein (His tag) Protein

SPAM1 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3081716
$10,223.08
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 1-509) protein (GST tag) Protein

SPAM1 Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1321070
$338.33
Plus shipping costs $45.00 and $24.00 dry ice
2 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 346-445) protein (GST tag) Protein

SPAM1 Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1321072
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

SPAM1 Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2732494
$504.90
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) protein (His tag) Protein

SPAM1 Origin: Human Source: HEK-293 Cells Recombinant ≥92 % by SDS-PAGE HPLC, SDS
Catalog No. ABIN1888707
$1,025.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-482) protein (His tag) Protein

SPAM1 Origin: Human Source: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
Catalog No. ABIN2181785
$1,375.00
Plus shipping costs $45.00
200 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) protein (Fc Tag) Protein

SPAM1 Origin: Human Source: HEK-293 Cells Recombinant
Catalog No. ABIN6964321
$433.23
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 17 to 18 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) protein (His tag) Protein

SPAM1 Origin: Human Source: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB
Catalog No. ABIN2566867
$639.38
Plus shipping costs $45.00
0.025 mg
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-491) protein (His tag) Protein

SPAM1 Origin: Cynomolgus Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1610527
$3,281.67
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days
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Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 36-492) protein (His tag) Protein

SPAM1 Origin: Guinea Pig Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1461869
$3,285.33
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days
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  • Type Protein
    • Protein
  • Target Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1)
    • Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • High Pressure Liquid Chromatography (HPLC)
    • Protein Interaction (PI)
    • Standard (STD)
    • Crystallization (Crys)
  • Reactivity
    • Human
    • Cynomolgus
    • Guinea Pig
  • Images available
  • Host
    • HEK-293 Cells
    • Wheat germ
    • Yeast
    • Insect Cells
  • Binding Specificity
    • AA 1-509
    • AA 346-445
    • AA 36-482
    • AA 36-490
    • AA 36-491
    • AA 36-492
    • Transcript Variant 1
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
    • Fc Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid

SPAM1 Protein Profile

Protein Summary

Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1\; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPAM1

  • sperm adhesion molecule 1 (Spam1) antibody
  • sperm adhesion molecule 1 (SPAM1) antibody
  • sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog (spam1.L) antibody
  • sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (SPAM1) antibody
  • sperm adhesion molecule 1 (spam1) antibody
  • AV039194 antibody
  • HYA1 antibody
  • HYAL1 antibody
  • HYAL3 antibody
  • HYAL5 antibody
  • im:6902904 antibody
  • PH-20 antibody
  • PH20 antibody
  • SPAG15 antibody
  • Spam antibody
  • spam1 antibody
  • XEH1 antibody
  • zgc:158668 antibody

Protein level used designations for SPAM1

hyal-PH20 , hyaluronidase PH-20 , hyaluronoglucosaminidase PH-20 , sperm surface protein PH-20 , sperm protein PH-20 , PH-20 protein , sperm surface antigen 2B1 , hyaluronidase , sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog , hyaluronidase, zona pellucida binding , sperm adhesion molecule 1

GENE ID SPECIES
20690 Mus musculus
100135624 Cavia porcellus
6677 Homo sapiens
100009391 Oryctolagus cuniculus
117037 Rattus norvegicus
398285 Xenopus laevis
353352 Bos taurus
791203 Danio rerio

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