Sperm Associated Antigen 6 Proteins

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization.

Data Quality
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Type
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    Protein
Target
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    Sperm Associated Antigen 6 (SPAG6)
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Application
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Reactivity
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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Suggested next Filters
4 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3077082
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3130312
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1321061
$338.33
2 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2732491
$932.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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Sperm Associated Antigen 6 (SPAG6) Protein Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPAG6

  • sperm associated antigen 6 (SPAG6) antibody
  • sperm associated antigen 6-like (Spag6l) antibody
  • sperm associated antigen 6 (Spag6) antibody
  • sperm associated antigen 6 (spag6) antibody
  • sperm associated antigen 6 L homeolog (spag6.L) antibody
  • DKFZp459D035 antibody
  • PF16 antibody
  • repro-sa-1 antibody
  • RGD1310892 antibody
  • SPAG6 antibody
  • zgc:91805 antibody

Protein level used designations for SPAG6

axoneme central apparatus protein , protein PF16 homolog , sperm flagellar protein , sperm-associated antigen 6 , axoneme protein , sperm associated antigen 6

GENE ID SPECIES
9576 Homo sapiens
50525 Mus musculus
360747 Rattus norvegicus
420505 Gallus gallus
431757 Danio rerio
450348 Pan troglodytes
477978 Canis lupus familiaris
539424 Bos taurus
548730 Xenopus (Silurana) tropicalis
734748 Xenopus laevis
100134839 Meleagris gallopavo
100174630 Pongo abelii
100286811 Sus scrofa
100724896 Cavia porcellus