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The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. Additionally we are shipping SPESP1 Antibodies (24) and SPESP1 Kits (7) and many more products for this protein.
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Equatorial segment protein (ESP), a novel 349-amino acid concanavalin-A-binding protein encoded by a two-exon gene (SP-ESP) located on chromosome 15 at q22, has been localized to the equatorial segment of ejaculated human sperm.
human alloantigen involved in sperm-egg binding and fusion
The present study identified SPESP1 in the acrosome as the primary binding target of Peanut agglutinin (PNA) in the mouse testis. Further defining the specific lectin-glycoprotein relationships in individual cells will enhance the value of lectin histochemistry.
These findings are consistent with the hypothesis that SPSPESP1 undergoes significant glycosylation in the testis and that the majority of these glycoconjugates are removed by the time sperm reach the caput epididymis.
SPESP1 is necessary to produce the fully 'fusion competent' sperm.
The encoded protein is a human alloantigen involved in sperm-egg binding and fusion.
sperm equatorial segment protein 1
, equatorial segment protein
, glycosylated 38 kDa sperm protein C-7/8