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SPESP1 Protein (His tag)

SPESP1 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319050
  • Target See all SPESP1 Proteins
    SPESP1 (Sperm Equatorial Segment Protein 1 (SPESP1))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This SPESP1 protein is labelled with His tag.
    Purpose
    Recombinant Human SPESP1 Protein (His Tag)
    Sequence
    Tyr20-Tyr350
    Characteristics
    Recombinant Human Sperm Equatorial Segment Protein 1 is produced by our Mammalian expression system and the target gene encoding Tyr20-Tyr350 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product SPESP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SPESP1 (Sperm Equatorial Segment Protein 1 (SPESP1))
    Alternative Name
    SPESP1 (SPESP1 Products)
    Synonyms
    ESP Protein, SP-ESP Protein, 4921508E09Rik Protein, AI428149 Protein, RGD1563468 Protein, sperm equatorial segment protein 1 Protein, SPESP1 Protein, Spesp1 Protein
    Background

    Background: Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis, it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may interact with IZUMO1 and MN9 antigen and it contains an N-glycosylation site as well as several cAMP-dependent kinase, protein kinase C, and casein kinase II consensus phosphorylation sites.

    Synonym: Sperm Equatorial Segment Protein 1, ESP, Equatorial Segment Protein, SP-ESP, Glycosylated 38 kDa Sperm Protein C-7/8, SPESP1

    Molecular Weight
    37.9 kDa
    UniProt
    Q6UW49
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