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Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. Additionally we are shipping SGPP1 Antibodies (31) and SGPP1 Proteins (4) and many more products for this protein.
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The two gastric cancer cells transfected with pEF-SGPP1 exhibited a slower rate of growth with less adhesion. Thus, our findings provided evidence that SGPP1 may serve as a prognostic biomarker for patients with advanced gastric cancers.
Study has revealed miR (show MLXIP ELISA Kits)-27a as a tumor suppressor and has identified SGPP1 and Smad2 (show SMAD2 ELISA Kits) as novel targets of miR (show MLXIP ELISA Kits)-27a, linking to STAT3 (show STAT3 ELISA Kits) for regulating cancer cell proliferation, apoptosis and migration in colorectal cancer.
The sphingolipid phosphatase SGPP1, an antagonist of sphingosine-1-phosphate signaling, is a target of miR (show MLXIP ELISA Kits)-95 that promotes radiation resistance.
S1P is elevated in patients with IPF, correlates with the lung function and mediates EMT (show ITK ELISA Kits).
doxorubicin switches protective autophagy in SPP1-depleted cells to apoptosis by calpain-mediated Atg5 cleavage.
SPP1 by regulating intracellular S1P homeostasis, can control the UPR and ER stress-induced autophagy.
sphingosine-1-phosphate phosphatase 1 plays roles in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability
sphingosine-1-phosphate phosphatase 1 has a role in epidermal growth factor (show EGF ELISA Kits)-induced chemotaxis
SPP-1 (show SPP1 ELISA Kits) regulates ceramide levels in the ER and thus influences the anterograde membrane transport of both ceramide and proteins from the ER to the Golgi apparatus.
Sphingosine kinase 2 (show SPHK2 ELISA Kits), but not sphingosine kinase 1 (show SPHK1 ELISA Kits), acted in concert with SPP-1 (show SPP1 ELISA Kits) to regulate recycling of sphingosine into ceramide.
Results show that Runx1 (show RUNX1 ELISA Kits) regulates glucocorticoid sensitivity in lymphoma cells and identify an established direct target gene, Sgpp1, as an integrator of sphingolipid metabolism and responses to glucocorticoids.
Data indicate that sphingosine-1-phosphate phosphatases 1 (Sgpp1) deficiency in keratinocytes causes sphingosine-1-phosphate (S1P) elevation and accelerates their differentiation.
regulation of sphingolipid metabolism and apoptosis by SPP1 (show SPP1 ELISA Kits)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000
sphingosine-1-phosphate phosphatase 1
, sphingosine-1-phosphatase 1
, sphingosine-1-phosphate phosphohydrolase